主 办:北 京 中 医 药 大 学
ISSN 2095-6606 CN 10-1157/R

现代中医临床 ›› 2021, Vol. 28 ›› Issue (1): 7-10.doi: 10.3969/j.issn.2095-6606.2021.01.002

• 临床研究 • 上一篇    下一篇

疏血通注射液辅助治疗青光眼视神经萎缩的疗效观察及

林婉儿1, 李昀熹1, 庞龙2#   

  1. 1 广州中医药大学第二临床医学院 广东 510405;
    2 广东省中医院眼科
  • 收稿日期:2020-05-20 出版日期:2021-01-30 发布日期:2021-02-02
  • 通讯作者: #庞龙,男,博士,主任医师、教授,博士生导师
  • 作者简介:林婉儿,女,在读硕士生
  • 基金资助:
    *广州市科技计划项目(No.201904010229)

Shuxuetong Injection as an adjuvant therapy for glaucomatous optic atrophy and evaluation of quality of life*

Lin Wan'er1, Li Yunxi1, Pang Long2#   

  1. 1 Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangdong 510405;
    2 Guangdong Provincial Hospital of Chinese Medicine
  • Received:2020-05-20 Online:2021-01-30 Published:2021-02-02

摘要: 目的 观察疏血通注射液辅助治疗青光眼视神经萎缩的疗效。方法 将64例青光眼视神经萎缩患者随机分为治疗组32例、对照组32例。剔除脱落病例后治疗组30例(60只眼)、对照组30例(58只眼)。对照组予甲钴胺片口服治疗,治疗组在予甲钴胺片口服的基础上,予疏血通注射液静脉滴注治疗。观察最佳矫正视力、视野平均缺损、生存质量量表评分。结果 2组最佳矫正视力治疗后较本组治疗前均提高(P<0.05),治疗组较对照组提高明显,2组治疗前后差值比较,差异有统计学意义(P<0.05),治疗组优于对照组。视野平均缺损治疗后治疗组较本组治疗前升高(P<0.05),对照组与本组治疗前比较差异无统计学意义(P>0.05)。视野平均缺损治疗后治疗组较对照组升高明显,2组治疗前后差值比较,差异有统计学意义(P<0.05),治疗组优于对照组。治疗组治疗后远视力、调节能力、读和精细动作、日常生活能力评分及生存质量量表评分总分较本组治疗前均提高,差异均有统计学意义(P<0.05)。对照组治疗后读和精细动作评分、生存质量量表评分总分较本组治疗前均提高,差异均有统计学意义(P<0.05)。远视力、调节能力、读和精细动作、日常生活能力评分及生存质量量表评分总分治疗组均较对照组提高明显,2组治疗前后差值比较,差异均有统计学意义(P<0.05),治疗组优于对照组。结论 疏血通注射液辅助治疗青光眼视神经萎缩具有较好的临床效果好,并能有效改善患者的生存质量。

关键词: 疏血通注射液, 青光眼, 视神经萎缩, 生活质量

Abstract: Objective To observe the effects of Shuxuetong Injection on glaucomatous optic atrophy. Methods 64 patients with glaucomatous optic atrophy were randomly divided into the treatment group(n=32) and control group(n=32). There were 30 cases (60 eyes) in the treatment group and 30 cases (58 eyes) in the control group after the shedding cases were excluded. All participants received MeCobalamin Tablets while the treatment group received additional Shuxuetong Injection. The best corrected visual acuity(BCVA), visual field mean deviation and Quality of Life Scale score were observed. Results BCVA improved significantly in both groups after treatment(P<0.05), significantly more in the treatment group than in the control group. Visual field mean deviation was significantly increased after treatment in the treatment group, but not in the control group, as compared with those before treatment (P>0.05). Visual field mean deviation was remarkedly increased, more in the treatment group than in the control group, and the differences in before-after treatments between the two groups were significant (P<0.05). And the scores of far vision, regulation ability, reading and fine movement, daily living ability and quality of life scale total scores all improved after treatment in the treatment group(P<0.05) while the scores of reading and fine movement quality of life scale total scores improved after treatment in the control group(P<0.05). Moreover, the improvements in scores of each dimension and total score of the quality of life scale were greater in the treatment group than in the control group(P<0.05). Conclusions Shuxuetong Injection can effectively improve the clinical symptoms and quality of life among patients with glaucomatous optic atrophy.

Key words: Shuxuetong Injection, glaucoma, nerve atrophy, quality of life

中图分类号: 

  • R276.7