YANG Zepei, HU Kaiwen, DING Zhiguo, et al. Clinical study of acupuncture in the treatment of hand-foot syndrome[J]. Modern Chinese Clinical Medicine, 2023, 30(4): 49-52,61.
DOI:
YANG Zepei, HU Kaiwen, DING Zhiguo, et al. Clinical study of acupuncture in the treatment of hand-foot syndrome[J]. Modern Chinese Clinical Medicine, 2023, 30(4): 49-52,61.DOI: 10.3969/j.issn.2095-6606.2023.04.010.
Clinical study of acupuncture in the treatment of hand-foot syndrome
To observe the clinical efficacy of acupuncture in the treatment of hand-foot syndrome (HFS).
Methods
2
20 patients with HFS were selected and given patient education and acupuncture (bilateral) for 3 weeks. Their efficacy and grading of HFS
HFS symptom scores
quality of life scores and safety were observed before and after treatment.
Results
2
After 3 weeks of treatment
2 cases were cured
12 cases were effective
and the total effective rate was 70%. After treatment
the scores of numbness
tingling sensation
insensitivity
burning sensation
pain
erythema
desquamation
pigmentation and swelling decreased significantly (
P
<
0.05). As for the EORTC QLQ-C30 score after treatment and before treatment
physical function
role function
emotional function
social function
fatigue
pain
loss of appetite
overall quality of life dimension scores were significantly improved (
P
<
0.05).
Conclusion
2
Acupuncture has a good clinical effect on HFS.
关键词
Keywords
references
LACOUTURE M E , SIBAUD V , GERBER P A , et al . Prevention and management of dermatological toxicities related to anticancer agents: ESMO clinical practice guidelines [J]. Ann of Oncol , 2021 , 32 ( 2 ): 157 - 170 .
DEGEN A , ALTER M , SCHENCK F , et al . The hand-foot-syndrome associated with medical tumor therapy - classification and management [J]. JDDG , 2010 , 8 ( 9 ): 652 - 661 .
YAP Y S , KWOK L L , SYN N , et al . Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial [J]. JAMA Oncol , 2017 , 3 ( 11 ): 1538 - 1545 .
SUZUKI S , NAWATA S , INADA Y , et al . A cross-sectional survey of methods for controling hand-foot syndrome in patients receiving capecitabine treatment [J]. Mol Clin Oncol , 2018 , 9 ( 4 ): 443 - 448 .
SON H S , LEE W Y , LEE W S , et al . Compliance and effective management of the hand-foot syndrome in colon cancer patients receiving capecitabine as adjuvant chemotherapy [J]. Yonsei Med J , 2009 , 50 ( 6 ): 796 - 802 .
UNITED STATES DEPARTMENT OF HEALTH AND HUMAN SERVICES . Common terminology criteria for adverse events (CTCAE) [EB/OL].[ 2022-08-06 ]. https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf .
STAROBOVA H , VETTER I . Pathophysiology of chemotherapy-induced peripheral neuropathy [J/OL]. Front Mol Neurosci , 2017 , 10 : 174 [ 2022-08-06 ]. https://www.frontiersin.org/articles/10.3389/fnmol.2017.00174/full https://www.frontiersin.org/articles/10.3389/fnmol.2017.00174/full .
ZIJLSTRA F J , VANDENBERG-DELANGE I , HUYGEN F J , et al . Anti-inflammatory actions of acupuncture [J]. Mediators Inflamm , 2003 , 12 ( 2 ): 59 - 69 .
LE J J , YI T , QI L , et al . Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression [J/OL]. Neuroscience Letters , 2016 , 615 : 66 - 71 [ 2022-08-06 ]. https://www.sciencedirect.com/science/article/abs/pii/S0304394016300040?via%3Dihub https://www.sciencedirect.com/science/article/abs/pii/S0304394016300040?via%3Dihub .
Discussion on the etiology,pathogenesis and prevention strategy of bladder cancer based on the theory of “ yang transforms into qi and yin constitutes form”
Pattern differentiation and treatment of male late-onset hypogonadism based on the theory of “zang-fu organs interconnection”
Analysis of regulating the Central Earth for depression treatment based on the Yiqi Zhouliu, Tushu Sixiang theory
Exploration of correlation between deep branch of ulnar nerve and palm acupoints
Analysis of outcome indexes of acupuncture treatment for functional constipation
Related Author
LIU Lihong
JI Rongfu
GAO Zhan
WEI Yi
HONG Zhiming
ZHOU Wenbin
WANG Quan
QIU Junfeng
Related Institution
Graduate School, Beijing University of Chinese Medicine
Xiyuan Hospital, China Academy of Chinese Medical Sciences
The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine
Shenzhen Traditional Chinese Medicine Hospital
School of Chinese Classics,Beijing University of Chinese Medicine