Traditional Chinese medicine treatment for migraine with aura related to patent foramen ovale by resolving constraint and harmonizing the spleen and stomach: a case report

WU Lianghui; LIN Keyi; QIU Yuhui

doi:10.3969/j.issn.2095-6606.2023.06.025

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Traditional Chinese medicine treatment for migraine with aura related to patent foramen ovale by resolving constraint and harmonizing the spleen and stomach: a case report

Case Reports | 更新时间：2023-12-08

- Traditional Chinese medicine treatment for migraine with aura related to patent foramen ovale by resolving constraint and harmonizing the spleen and stomach: a case report
- Modern Chinese Clinical Medicine Vol. 30, Issue 6, Pages: 113-116(2023)
- 作者机构：
  
  1.广州中医药大学第二临床医学院　广州　510405
  2.广东省中医院
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2095-6606.2023.06.025
  CLC： R249
- Received：23 September 2022，
  
  Published：30 November 2023
- 稿件说明：
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WU Lianghui, LIN Keyi, QIU Yuhui. Traditional Chinese medicine treatment for migraine with aura related to patent foramen ovale by resolving constraint and harmonizing the spleen and stomach: a case report[J]. Modern Chinese Clinical Medicine, 2023, 30(6): 113-116.
DOI：

WU Lianghui, LIN Keyi, QIU Yuhui. Traditional Chinese medicine treatment for migraine with aura related to patent foramen ovale by resolving constraint and harmonizing the spleen and stomach: a case report[J]. Modern Chinese Clinical Medicine, 2023, 30(6): 113-116. DOI： 10.3969/j.issn.2095-6606.2023.06.025.

摘要

卵圆孔未闭(patent foramen ovale，PFO)是一种先天性心脏异常，因出生后房间隔未完全融合而引起。PFO与先兆性偏头痛(MA)的发生密切相关。目前PFO引起偏头痛的发病机制尚不明确，治疗以卵圆孔封堵术及发作期止痛治疗为主。运用解郁和中法治疗PFO相关MA 1例，取得满意疗效，随访1年头痛及先兆未再发作，提示器质性改变并非本病单一发病因素，药物改善患者功能或易感性可成为本病治疗方案，并为中医治疗该病提供思路。

Abstract

Patent foramen ovale (PFO) is a congenital cardiac anomaly caused by incomplete fusion of the atrial septum after birth. PFO is closely associated with the development of migraine with aura (MA). The pathogenesis of PFO-induced migraine is still unclear

and the treatment is based on PFO closure and pain relief treatment during attacks. One case of PFO-associated MA was treated with TCM herbal medicine by resolving constraint and harmonizing the spleen and stomach

which achieved satisfactory efficacy

and the headache and aura did not reoccur in 1 year of follow-up

suggesting that organic changes are not the single pathogenetic factor of the disease

and that medications to improve the patient’s function or susceptibility can be a treatment option for the disease. This could provide some ideas for TCM treatment of the disease.

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Keywords

references

WANG S B ， LIU K D ， YANG Y ， et al . Prevalence and extent of right-to-left shunt on contrast-enhanced transcranial Doppler in Chinese patients with migraine in a multicentre case-control study [J]. Cephalalgia ， 2018 , 38 ( 4 ): 690 - 696 .

LIU K ， WANG B Z ， HAO Y ， et al . The correlation between migraine and patent foramen ovale [J/OL]. Front Neurol ， 2020 , 11 : 543485 [ 2022-09-23 ]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736411/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736411/ .

ZHANG Q Q ， LU J J ， YAN M Y ， et al . The efficacy of percutaneous patent foramen ovale closure on migraine: a meta-analysis of randomized controlled trials and observational studies [J/OL]. Biomed Res Int ， 2021 , 2021 : 6643266 [ 2022-09-23 ]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954613/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954613/ .

刘凯，赵嘉玮，张锐，等 . 偏头痛与卵圆孔未闭研究进展 [J]. 中国现代神经疾病杂志， 2021 , 21 ( 1 ): 53 - 57 .

宋婷婷，彭安娇，李宛凌，等 . 卵圆孔未闭与偏头痛的相关性研究进展 [J]. 中国临床神经科学， 2021 , 29 ( 3 ): 315 - 320 .

GUO Y ， SHI Y ， ZHU D ， et al . Clopidogrel can be an effective complementary prophylactic for drug-refractory migraine with patent foramen ovale [J]. J Investig Med ， 2020 , 68 ( 7 ): 1250 - 1255 .

KHASIYEV F ， ARSAVA E M ， TOPCUOGLU M A . Cerebral vasomotor reactivity in migraine: effect of patent foramen ovale and aerogenic microembolism [J]. Neurol Res ， 2020 , 42 ( 9 ): 795 - 804 .

ZHAO Q ， LIU R ， ZHOU J ， et al . Prevalence and grade of RLS in migraine: A prospective study of 251 migraineurs by synchronous test of c-TTE and c-TCD [J/OL]. Medicine (baltimore) ， 2021 , 100 ( 4 ): e24175 [ 2022-09-23 ]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850732/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850732/ .

DOWSON A ， MULLEN M J ， PEATFIELD R ， et al . Migraine Intervention With STARFlex Technology(MIST) trial: a prospective，multicenter，double-blind，sham-controlled trial to evaluate the effectiveness of patent foramen ovale closure with STARFlex septal repair implant to resolve refractory migraine headache [J]. Circulation ， 2008 , 117 ( 11 ): 1397 - 1404 .

MATTLE H P ， EVERS S ， HILDICK-SMITH D ， et al . Percutaneous closure of patent foramen ovale in migraine with aura，a randomized controlled trial [J]. Eur Heart J ， 2016 , 37 ( 26 ): 2029 - 2036 .

TOBIS J M ， CHARLES A ， SILBERSTEIN S D ， et al . Percutaneous closure of patent foramen ovale in patients with migraine: the PREMIUM trial [J]. J Am Coll Cardiol ， 2017 , 70 ( 22 ): 2766 - 2774 .

张玉顺，朱鲜阳，蒋世良，等 . 卵圆孔未闭处理策略中国专家建议 [J]. 心脏杂志， 2015 , 27 ( 4 ): 373 - 379 .

PRISTIPINO C ， GERMONPRÉ P ， TONI D ， et al . European position paper on the management of patients with patent foramen ovale. Part II － Decompression sickness，migraine，arterial deoxygenation syndromes and select high-risk clinical conditions [J]. EuroIntervention ， 2021 , 17 ( 5 ): e367 - e375 .

HEADACHE CLASSIFICATION SUBCOMMITTEE OD THE INTERNATIONAL HEADACHE SOCIETY . The international classification of headache disorders: 3rd edition [J]. Cephalalgia ， 2018 , 38 ( 1 ): 122 - 125 .

张云云，吴波水，刘毅 . 中国偏头痛中西医结合防治指南(2022年) [J/OL]. 中国中西医结合杂志， 2023 : 1 - 10 ( 2023-05-09 ). https://kns.cnki.net/kcms/detail/11.2787.r.20230508.0915.004.html https://kns.cnki.net/kcms/detail/11.2787.r.20230508.0915.004.html .

张璐 . 张氏医通 [M]. 太原：山西科学技术出版社 , 2010 : 111 - 114 .

韩笑，邹忆怀，李匡时，等 . 针刺足临泣对偏头痛患者大脑皮层局部一致性影响的研究 [J]. 现代中医临床， 2017 , 24 ( 6 ): 31 - 35,65 .

樊欢欢，张丹莉，张凯歌，等 . 从玄府气液理论探讨偏头痛的病机及治疗 [J]. 现代中医临床， 2022 , 29 ( 2 ): 38 - 42 .

华荣，曾茜，侯紫君，等 . 调畅肝、脾、胃气机论治偏头痛经验 [J]. 中医研究， 2016 , 29 ( 6 ): 45 - 47 .

揭珊珊，李语婕，梁晓涛，等 . 偏头痛先兆临床表现综述 [J]. 中华神经医学杂志， 2020 , 19 ( 5 ): 537 - 540 .

张仲景 . 金匮要略 [M]. 李辰，郝阳，周劲草，校注 . 北京：中国医药科技出版社 , 2018 : 1 .

李东垣 . 兰室秘藏 [M]. 张年顺，校注. 北京：中国中医药出版社 , 2007 : 31 .

文灼彬，华荣 . 华荣应用健脾调畅气机法治疗经行头痛经验 [J]. 西部中医药， 2018 , 31 ( 10 ): 19 - 21 .

王玭，华荣 . 基于脑fMRI对偏头痛再认识及解郁和中法辨治偏头痛经验 [J]. 湖南中医药大学学报， 2018 , 38 ( 9 ): 1028 - 1031 .

何莉娜，孙景波，华荣 . 349例头风病患者证候观察 [J]. 辽宁中医药大学学报， 2010 , 12 ( 1 ): 136 - 137 .

王玭，华荣，王道弘，等 . 解郁和中汤辨治肝脾胃失调型偏头痛疼痛矩阵局部一致性fMRI研究 [J]. 中华中医药杂志， 2020 , 35 ( 8 ): 4218 - 4221 .

郭歆，武曼丽，丘宇慧，等 . 199例女性偏头痛患者舌象分析与中医核心病机探讨 [J]. 湖南中医药大学学报， 2020 , 40 ( 4 ): 440 - 444 .

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