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影响因子：1.174 ISSN：2095-6606CN：10-1157/R 出版周期：Bimonthly 邮箱：xdzylc@bucm.edu.cn最新刊期：2025年 第6期
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Special Feature on TCM Treatment for Tumors and Associated Diseases
“在胃癌治疗领域，本团队基于“调平”理论，将新加良附方与健脾益气方合用，有效提升晚期胃癌患者生存质量。”摘要：Gastric cancer(GC)is one of the common malignant tumors of the digestive tract. Maintenance therapy is an important part of the current staged treatment for GC, aiming to stabilize disease, reduce recurrence, and prolong patient survival. Traditional Chinese Medicine(TCM)can improve the overall treatment response rate, relieve symptoms, and improve quality of life in advanced cases. Our team has proposed the Tiaoping theory, which primarily includes two aspects:harmonizing and gentle regulation. The former intends to restore the patient's internal balance of qi, blood, yin, and yang, promoting disease cure or remission. The latter advocates that treatment method should be calm and gentle, minimizing the use of toxic or aggressive herbs and other confrontational therapies, and taking care of the healthy qi as much as possible. Guided by the Tiaoping theory, our team combines the Newly Supplemented Liangfu Formula(Newly Supplemented Lesser Galangal and Cyperus Formula)with the Jianpi Yiqi Formula(Spleen-Fortifying and Qi-Boosting Formula)to jointly achieve the effects of strengthening the spleen, warming the stomach, regulating qi, and removing blood stasis, while also strengthening resistance and eliminating pathogenic factors. Its anti-tumor mechanisms are clear and its clinical efficacy is significant. This article will elaborate on the application of Newly Supplemented Liangfu Plus Jianpi Yiqi Formula guided by the theory of Tiaoping in the maintenance treatment of advanced GC, supported by clinical cases, for clinical reference.关键词：TiaoPing theory;advanced gastric cancer;Newly Supplemented Liangfu Plus Jianpi Yiqi Formula;maintenance treatment;traditional Chinese medicine134|35|0<引用本文> <批量引用>更新时间：2025-12-12Special Feature on TCM Treatment for Tumors and Associated Diseases
“在食管癌治疗领域，专家基于圆运动理论，提出了新的辨治思路和方法，为临床治疗提供了新方案。”摘要：Esophageal carcinoma is a frequently encountered malignant neoplasm with high lethality and atypical early manifestations. In the circular qi movement of the human body, the interplay of yin and yang can be conceptualized as a“qi-transformation versus form-formation”dynamic characterized by the ascent of yang and the descent of yin. Pathogenetically, this circular paradigm implicates three interlocking mechanisms in esophageal carcinogenesis:insufficient ascent of yang qi, depriving the“axis-and-wheel”motion of its motive power; aberrant descent of yin, leading to the entrenchment of phlegm and static blood that obstructs the circulation; failure of the axis-wheel rotation, permitting neoplastic toxin to arise and disseminate. Corresponding therapeutic strategies based on the Circular Motion theory comprise:fortifying the spleen, dispersing the liver, and warming the kidney to initiate the ascent and outward floating of yang; dissipating phlegm-stasis and unblocking the collaterals to break the descent and inward precipitation of yin. Clinical cases are integrated to elucidate the diagnostic and therapeutic application of this Circular Motion approach to esophageal carcinoma.关键词：esophageal cancer;Circular Motion;TCM pattern differentiation and treatment97|38|0<引用本文> <批量引用>更新时间：2025-12-12Special Feature on TCM Treatment for Tumors and Associated Diseases
“在恶性肿瘤血液高凝状态治疗领域，王清任“气血合脉说”提供了新思路，通过逐瘀活血法和补气活血法，为临床治疗提供有效方案。”摘要：Hypercoagulable state (HCS)can induce abnormal intravascular coagulation, leading to varying degrees of vascular occlusion and venous thromboembolism. The theory of qi-blood and vessel coordination proposed by Wang Qingren elucidates the synergistic relationship between qi and blood, emphasizing that the key to treatment lies in differentiating deficiency and excess patterns of qi and blood. Malignancy-associated hypercoagulability demonstrates close correlation with the blood stasis pattern. The core pathogenesis of malignant HCS lies in toxin impairment of qi-blood with internal blood stasis retention. This condition manifests as root deficiency with superficial excess, where deficiency of vital qi constitutes the fundamental etiology of malignancies, while both cancerous toxins and chemotherapeutic agents directly damage qi and blood. Based on the theory of qi-blood and vessel coordination, two therapeutic approaches are applied for malignant HCS:blood stasis-removing and blood-activating method, as well as qi-tonifying and blood-activating method. The former is exemplified by Wang's Wuzhuyu Decoction (Five Stasis-Resolving Decoction), tailored according to the specific anatomical locations of stasis accumulation. In contrast to the purgative and attacking nature of stasis-removing therapy, the qi-tonifying approach prioritizes supplementation, typically employing the Buyang Huanwu Decoction (Yang-Supplementing and Five-Returning Decoction). This paper elaborates on the management of malignancy-induced hypercoagulability guided by the theory of qi-blood and vessel coordination through clinical case analyses.关键词：malignant tumors;hypercoagulable state;blood stasis;qi-blood and vessel coordination;theoretical discussion90|28|0<引用本文> <批量引用>更新时间：2025-12-12Special Feature on TCM Treatment for Tumors and Associated Diseases
“恶性肿瘤治疗新进展：专家提出“司揣内外”双重辨证体系，为肿瘤治疗提供新方案。”摘要：The core pathogenesis of malignant tumors is the internal amassment of yang toxin and the external formation of nests by phlegm and stasis, which combine to become toxin. Based on the exploration and application of“inspecting and conjecturing the exterior and interior”by ancient and modern physicians, this paper summarizes and proposes that“inspecting the interior”aims to grasp the core pathogenesis of malignant tumors and judge their transmission and prognosis, while“conjecturing the exterior”involves judging the progression of the disease during treatment based on the characteristics of tumor onset, consistently applying“cancer-removing and toxin-resolving” throughout the disease treatment to directly target the illness. Simultaneously, by combining the pattern identification concept of“inspecting and conjecturing the exterior and interior”, modifications are made according to the pattern, ultimately achieving the purpose of pattern identification and treatment of tumors through“inspecting and conjecturing the exterior and interior”. A clinical case is also included to illustrate the application of the dual pattern identification system of“inspecting and conjecturing the exterior and interior”in malignant tumors.关键词：inspecting and conjecturing the interior and exterior;inspecting the interior to conjecture the exterior;inspecting the exterior to conjecture the interior;core pathogenesis;malignant tumor92|22|0<引用本文> <批量引用>更新时间：2025-12-12Clinical Research
“在功能性便秘治疗领域，专家分析了针刺疗法的临床研究现状，指出结局指标应用存在问题，为构建核心指标集提供参考。”摘要：Objective To analyze the application and current status of outcome indicators in randomized controlled trials (RCTs)of acupuncture in treatment of functional constipation, and to provide useful reference for clinical study design of the construction of a core outcome indicator set. Methods Clinical studies included in 10 databases including CNKI and Embase from October 1,2019 to July 12,2024 were collected to extract, summarize and analyze relevant outcome indicators. The indicator domains of acupuncture in the treatment of functional constipation were sorted out. Results A total of 23 articles were included, covering 37 outcome indicators. Among them, symptom/signs (72.73%)were the most frequently used, followed by quality of life (9.10%), safety events (8.18%), physical and chemical tests (5.45%), Traditional Chinese Medicine syndromes (3.64%), and long-term prognosis (0.90%). None of the articles included economic evaluation indicators. There was no distinction in priority among the outcome indicators for randomized controlled trials of acupuncture treatment for functional constipation. The evaluation criteria for clinical efficacy were not unified, the safety evaluation reports were not standardized, and the reports of economic evaluation indicators were scarce. Conclusion This study serves to standardize the core measurement tools for clinical trials of Traditional Chinese Medicine, provide current most recognized and reliable measurement tools, implementation guidelines, and time points for each indicator.关键词：functional constipation;acupuncture;randomized controlled trial;outcome measures;subgroup analysis44|17|0<引用本文> <批量引用>更新时间：2025-12-12Clinical Research
“在肥胖治疗领域，研究者通过中药联合穴位埋线疗法，有效控制体重，提高基础代谢，改善症状，安全性良好。”摘要：Objective To observe the clinical effect of TCM herbal medicine therapy combined with acupoint catgut embedding therapy in treating simple obesity. Methods A total of 80 patients diagnosed with simple obesity with spleen deficiency leading to failure of transportation were recruited and randomly divided into a treatment group and a control group, with 40 in each. The control group was given Shenling Baizhu Powder (Ginseng, Poria and Atractylodes Macrocephalae Powder)combined with Fangji Huangqi Decoction (Stephania Root and Astragalus Decoction), while the treatment group received acupoint catgut embedding therapy combined with the same herbal medications. The intervention lasted for 30 days. Before and after treatment, the participants'TCM pattern scores were obtained, and DBA-550 body composition analyzers were used to analyze their body composition, obesity, basal metabolism, and total body scores. The clinical efficacy of the two groups was compared and the adverse reactions during treatment were recorded. Results The total water, body fat mass, body weight, BMI, fat percentage, hip-waist ratio and visceral fat area in the treatment group were significantly lower than those in the control group (P<0.05). Muscle mass, fat-free weight, basal metabolism and total body score were significantly higher than those in the control group (P<0.05). In terms of TCM pattern scores, the treatment group was lower than the control group (P<0.05). Overall speaking, the total effective rate of the treatment group (97.5%)was higher than that of the control group (92.5%), and the difference was statistically significant (P<0.01). There were no obvious adverse reactions in both groups. Conclusion TCM herbal medicine combined with acupoint catgut embedding in the treatment of simple obesity can effectively control patients'weight, increase basal metabolism and improve clinical symptoms, with desirable overall safety.关键词：human body composition analysis;acupoint catgut embedding therapy;Shenling Baizhu Powder;Fangji Huangqi Decoction;simple obesity56|30|0<引用本文> <批量引用>更新时间：2025-12-12Clinical Research
“最新研究发现，手掌穴位的穴感强度与尺神经阻滞程度密切相关，证实了肌门、骨门作为穴位实体解剖结构的观点。”摘要：Objective To explore the relationship between acupoints in the palm and hilus of muscle, hilus of bone, and nerves by comparing the intensity of acupoint sensations in the palm before and after ulnar nerve blockinvivo. Methods Thisstudywasdividedintotwogroups:incompleteulnarnerveblock (Experiment 1)and complete ulnar nerve block (Experiment 2). Anesthesia was achieved by injecting 2% lidocaine and 1% ropivacaine into the ulnar nerve groove at the elbow. Eight acupoints in the palm, namely Erjian (LI 2), Sanjian (LI 3), Hegu (LI 4), Laogong (PC 8), Zhongzhu (SJ 3), Shaofu (HT 8), Yuji (LU 10), and Houxi (SI 3), were selected. Acupuncture was performed before and after the onset of anesthesia, and the acupoint sensations was evaluated using the Chinese version of Massachusetts General Hospital Acupuncture Sensation Scale (C-MASS). Statistical analysis was conducted on the acupoint sensations before and after anesthesia. The anesthetic effects of Experiment 1 and Experiment 2 were evaluated based on the motor and sensory functions of the ulnar nerve distribution area. Results In Experiment 1, with incomplete ulnar nerve block, the acupoint sensations at Sanjian, Hegu, Zhongzhu, Shaofu, Laogong, and Houxi decreased after anesthesia (P<0.05), with statistically significant difference, while there was no significant difference in the acupoint sensations at Erjian and Yuji compared to before anesthesia (P>0.05), with statistically significant difference. In Experiment 2, with complete ulnar nerve block, the acupoint sensations at Hegu, Zhongzhu, Houxi, and Shaofu disappeared after anesthesia, the acupoint sensations at Sanjian and Laogong decreased, and there was no significant difference in the acupoint sensations at Erjian and Yuji compared to before anesthesia (P>0.05). Conclusion The generation and conduction of acupoint sensations are closely related to nerves, which is consistent with the view that hilus of muscle and hilus of bone are the physical anatomical structures of acupoints.关键词：ulnar nerve;acupoint;anesthesia;acupoint sensations;acupuncture;hilus of muscle and hilus of bone47|14|0<引用本文> <批量引用>更新时间：2025-12-12Clinical Research
“最新研究发现，肛肠坐浴方能有效降低高位复杂肛瘘术后患者创面早期炎症反应，加速创面愈合，提升患者生活质量。”摘要：Objective To investigate the effect of Gangchang Sitting Bath Prescription on early inflammatory response in patients undergoing high-frequency electric knife high complex anal fistula surgery. Methods Seventy patients who underwent surgery for high-position complex anal fistula at the Department of Anorectal Surgery, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, from February 2022 to April 2024 were randomly divided into a control group and a treatment group, with 35 patients in each, using a random number table method. The control group received washing treatment with 3% boric acid solution detergent soaking, while the treatment group received washing treatment with Gangchang Sitting Bath Prescription twice a day until the wound was completely healed. Several indicator were observed and compared between two groups on postoperative days 1 and 7, including clinical symptoms of wound exudation, wound pain, and granulation tissue growth, quality of life (QOL)scores, levels of (tumor necrosis factor-α, TNF-α), (interleukin-6, IL-6)in wound secretions and (vascular endothelial growth factor, VEGF)in wound granulation tissue, and the wound healing time. Results On postoperative day 1, there was no statistically significant difference in wound exudation, granulation tissue, and wound pain between the two groups of patients (P>0.05). On postoperative day 7, the wound exudation, granulation tissue, and wound pain scores in the treatment group were lower than those in the control group, and the difference was statistically significant (P<0.01). On postoperative day 1, there was no statistically significant difference in QOL scores between the two groups, including pain, mental state, sleep, and daily life scores (P>0.05). On postoperative day 7, the treatment group had higher scores in pain, mental state, sleep, and daily life than the control group, and the difference was statistically significant (P<0.01). The wound healing time of the treatment group was shorter than that of the control group, and the difference was statistically significant (P<0.01). On postoperative day 1, there was no statistically significant difference in the expression levels ofTNF-α, IL-6 in wound secretions and VEGF in wound granulation tissue between the two groups of patients (P>0.05). On postoperative day 7, the levels of TNF-α and IL-6 in wound secretions of the treatment group were lower than those of the control group, and the difference was statistically significant (P<0.01). The expression level of VEGF in wound granulation tissue of the treatment group was higher than that of the control group, and the difference was statistically significant (P<0.01). Conclusion Gangchang Sitting Bath Prescription can reduce early inflammatory response of the wound, accelerate the transition from the inflammatory phase to the proliferative phase, promote the resolution of related clinical symptoms, accelerate the wound healing process, and effectively improve the quality of life of patients after high-frequency electric knife surgery for high-position complex anal fistula.关键词：Gangchang Sitting Bath Prescription;high-frequency electric knife;high-position complex anal fistula;postoperative;inflammatory response75|23|0<引用本文> <批量引用>更新时间：2025-12-12
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