摘要:Objective To investigate the antagonistic mechanism of Compound Xiancao Mixture to endothelial cell lesion. Method The model of endothelial cell lesion of atherosclerosis was established by using high fat feed and immune lesion in rabbits. To observe the influence of Compound Xiancao Mixture on the expression of nitricoxide synthase (NOS) gene in endothelial cells by in situ hybridization. Result The sludging of brown granules in endothelial cells and smooth muscle cytochylema in the high-dose group and low-dose group were obvious increased than that in the model group. Conclusion Compound Xiancao Mixture has an improvement effect on the expression of NOS gene. The mechanism maybe related to its antagonism to cell lesion of atherosclerosis through regulating NOS and improving NO release.
摘要:Objective To observe the curative effect of gingko flavonoid glycosides (ginkgo leaf extract, EGB761) on interstitial pulmonary fibrosis (IPF) and the correlation between the curative effect and immune cytokines. Method The patients with IPF (n=45) were randomly divided into two groups. Group 1 was given Yinxingye Capsules orally and group 2 was given prednisone for 3 months respectively. The relief of symptoms and improvement of lung function, the changes of interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α) were observed before and after the treatment. Result The total effective rate was 80.00% in group 1 and that in group 2, 66.67 %. There were significant differences (P<0.05) in the total lung capacity (TLC), vital capacity (VC), diffusing capacity (Dlco), IL-6, IL-8 and TNF-α in two groups before and after the treatment. Conclusion Gingko flavonoid glycosides has a curative effect on IPF and has the correlation with immune cytokines.
摘要:Objective To find out some prescriptions of Chinese medicine with better curative effect on child asthma. Method With the random control method group 1 (n=51) was given Inhaled Seretide and Yiqibushenhuoxue Decoction and group 2 (n=51) was given Inhaled Seretide only, and then the curative effects of two groups were observed and compared. Result The total effective rate of group 1 was 96.07 % and that of group 2, 84.31 %. The curative effect of group 1 was better than that of group 2 (P<0.05). The improvement of lung function in group 1 was better than that in group 2 (P<0.01). Conclusion Yiqibushenhuoxue Decoction has a reliable curative effect on child asthma.
摘要:Objective To investigate the curative effect of the therapy of nourishing yin and astringing yang on senile insomnia of the syndrome type of hyperactivity of yang due to yin-deficiency. Method The therapy of nourishing yin and astringing yang was used to treat 32 cases of senile insomnia of the syndrome type of hyperactivity of yang due to yin-deficiency. The changes of the time for falling asleep, sleep quality and sleep time were observed. Result After the treatment the time for falling asleep was shortened, the sleep quality was improved and the sleep time was prolonged (P<0.01). The total effective rate was 87 %. Conclusion The therapy of nourishing yin and astringing yang has a better curative effect on senile insomnia of the syndrome type of hyperactivity of yang due to yin-deficiency.
关键词:insomnia;hyperactivity of yang due to yin-deficiency;nourishing yin and astringing yang
摘要:Objective To observe the curative effect of Xuefuzhuyu Decoction on psoriasis vulgaris and its influence on the hemorrheology. Method To divide randomly 60 patients into two groups. The treatment group was given Xuefuzhuyu Decoction orally and the control group was given Fufangqingdai Capsules orally. The treatment course was 8 weeks. The curative effect and relative examine indexes were observed. Result After the treatment the integral of rash in the treatment group was better than that in the control group (P<0.01). The obvious effect rates of two groups were 76.6 % and 43.33 % respectively. The difference of two groups was significant and the curative effect of the treatment group was better than that of the control group (P<0.05). The hemorrheology was changed remarkably in the treatment group after the treatment(P<0.01). Conclusion Xuefuzhuyu Decoction has a better curative effect on psoriasis vulgaris. It can improve the microcirculation, body immunity and the recovery of skin injury.
摘要:Objective To observe the curative effect of Xinkeshu Tablets on sinus tachycardia (ST) of inorganic cardiopathy. Method To treat 36 cases of ST of inorganic cardiopathy with Xinkeshu Tablets with 4 tablets three times daily. A treatment course was 4 weeks. The heart rate, changes of biochemical test and start time of the drug effect were observed. Result There were 22 cases with obvious effect and 8 with effect. The total effective rate was 83.33%. The influence of Xinkeshu Tablets on the heart rate began from the second week and Xinkeshu Tablets had the best effect during the third to fifth week. Conclusion Xinkeshu Tablets can inhibit ST of inorganic cardiopathy. The drug is safe and has no side effects.
摘要:Objective To observe the curative effect of Chinese medicine on primary fibromyalgia syndrome (PFS). Method The oral Xianweijitong Mixture and its modifications, acupuncture and massage were given to 197 cases of PFS diagnosed by different hospitals in Germany, and the pain indexes, other physical signs and dose changes of obtundents were observed. Result There were 42 cases with an obvious effect, 91, with a curative effect, and the total effective rate was 67.5 %. The mean of pain indexes decreased(P<0.05),and symptoms and signs were relieved remarkably after the treatment. There were 103 cases were given less dose of obtundents or stopped the drug. Conclusion The comprehensive treatment of PFS with Chinese medicine has a better curative effect.
关键词:soothing liver to regulate qi;replenishing qi to activate blood;regulating qi and removing stasis;invigorating spleen to resolve dampness;nourishing blood to tranquilize mind;primary fibromyalgia syndrome
摘要:Objective To observe the curative effect of warm moxibustion at Zhiyang (GV9) on cold epigastrolgia. Method To divide randomly 120 patients into the treatment group and the control group. The treatment group(n=62) was treated with warm moxibustion at Zhiyang (GV9) and the control group(n=58) was treated with needling in Zhiyang (GV9), Zusanli (ST36) and TDP radiation. Result The total effective rate of the treatment group was 96.8 % and that of the control group, 75.9 %. The curative effect of the treatment group was better than that of the control group (P<0.01). Conclusion The treatment of cold epigastralgia with warm moxibustion at Zhiyang (GV9) has a reliable curative effect.