摘要:Objective To observe the curative effect of Maitongling Mixture on arteriosclerosis obliteration (ASO, gangrene of finger or toe, Chinese medical syndrome of yin-damage by heat toxin). Method To choose the patients with diagnosed ASO (gangrene of finger or toe, syndrome of yin-damage by heat toxin) and give them the treatment with Maitongling Mixture. The curative effect was observed and summed up. Result There were 28 cases cured, 35 with significant curative effect, 10 with effect, 2 without effect and 2 deteriorated. The total effective rate was 91.25 %. The himorrheological indexes and symptoms, such as cool feeling on the skin, intermittent claudication, rest pain and ulcerous healing were relieved obviously (P<0.01). Conclusion Maitongling Mixture is effective and safe for the treatment of arteriosclerosis obliteration.
关键词:Maitongling Mixture;arteriosclerosis obliteration;syndrome of yin-damage by heat toxin;clearing away heat and resolving toxin;nourishing yin and dredging collaterals
摘要:Objective To investigate the curative effect of Jianpixiaozhang Granules on functional dyspopepsia. Method To divide randomly 120 patients with functional dyspopepsia (syndrome of sleen-insufficiency and qi-stagnation) into the treatment group (n=60) and the control group (n=60). The treatment group was treated with Jianpixiaozhang Granules and blank control tablets, and the control group was treated with Mosapride Tablets and simulated Jianpixiaozhang Granules for 4 weeks respectively. Result The symptoms of two groups after the treatment were significantly relieved than before the treatment (P<0.05). The gastric evacuation rates of two groups after the treatment were much better than before the treatment (P<0.05). Conclusion Jianpixiaozhang Granules has the similar effects with Mosapride Tablets in the relieving of symptoms and the improvement of gastric evacuation in the patients with functional dyspopepsia (syndrome of sleen-insufficiency and qi-stagnation).
关键词:Jianpixiaozhang Granules;functional dyspopepsia;gastroenteric motor;strengthening spleen and replenishing qi;regulating qi and relieving stagnation
摘要:Objective To investigate the syndrome characteristics of Chinese medicine (CM) and relative factors in the patients with diabetes mellitus (DM). Method The questionnaires were used to survey the symptoms of DM patients and the CM syndromes were determined. At the same time the general states, outcomes of different biochemistry examinations and questions related to DM were investigated and treated statistically. Result In DM patients the syndromes of kidney-deficiency, excessive phlegm-dampness or blood stasis were most common, and syndromes of yin-deficiency and qi-insufficiency were accounted for a quite large proportion. The ratio of relative multiple syndromes was higher, while the syndrome of dryness-heat was not as common as traditional cognition. Conclusion It should be paid attention by the clinical physicians that there are many changes in the CM syndrome characteristics in DM patients compared with the traditional knowledge.
关键词:diabetes mellitus;syndrome of Chinese medicine;relative factors
摘要:Objective To study the inhibitory mechanism of genistein on extracorporeal proliferation of ishikawa cells of human endometrial cancer cell line. Methods Ishikawa cells of human endometrial cancer cell line were cultured in vitro and then the proliferation of cells by MTT method and cell cycle was detected by flow cytometry. Result Genistein inhibited the proliferation of ishikawa cells in vitro with a characteristic of dose-dependence. The higher of genistein concentration was, the more remarkable of genistein effect was. The inhibitory effect was most obviously 48 hours after the administration of genistein. After 72 hours the inhibitory rate was increased slightly without significance and after 96 hours it was decreased slightly. The inhibitory rate was significantly decreased 120 hours after the administration of genistein. Ishikawa cells effected by genistein were blocked in G2-M phase significantly. Conclusion Genistein can inhibit the extracorporeal proliferation of ishikawa cells through blocking the cells in G2-M phase.
摘要:Objective To investigate the effective mechanism of Qingfei Decoction combined with Bailing Capsules on rats in acute phase of asthma. Method The animal model of asthma was established with SD rats and then divide them into the group 1 (normal control group), group 2 (model group), group 3 (Qingfei Decoction combined with Bailing Capsules group), group 4 (Qingfei Decoction group) and group 5 (dexamethasone group, each n=10). The pathological changes in lung tissue were observed in different groups. Result In group 3 the inflammation was relieved. There was no inflammation observed on respiratory tract wall. The lymphocyte infiltration was obviously decreased and stenosis of bronchocavity was not observed. The curative effect in group 3 was better than that in group 4 and group 5. Conclusion Bailing Capsules can relieve more quickly the bronchospasm and inflammation, decrease eosinophils (EOS) infiltration and inhibit the hyperergy of respiratory tract.
关键词:tonifying kidney;Qingfei Decoction;Bailing Capsules;acute phase of asthma;pathology;rats
摘要:Objective To observe the influence of electroacupuncture on interleukin-6 (IL-6) and interleukin-10 (IL-10) in rats with local cerebral ischemia-reperfusion and investigate the mechanism of acupuncture for treating cerebral ischemia lesion. Method The model of middle cerebral artery obstruction (MCAO) was established in SD rats by using intraluminal suture. After 2 hours the suture was withdrawn to induce reperfusion lesion. The changes of IL-6 and IL-10 contents were observed in rat plasma and cerebral tissue at different time points and after the treatment of electroacupuncture. Result The contents of IL-6 and IL-10 were increased in the treatment group 1 than that in the control group 1 (P<0.05). The content of IL-6 in the treatment group 2 was increased than that in the control group 2 (P<0.05). There was a significant difference in IL-10 content between the treatment group 1 and control group 1 (P<0.05). Conclusion Electroacupuncture can inhibit the aggregation and activation of inflammatory cells and the release of cell toxic materials in ischemia area through improving the expressions of IL-6 and IL-10 to a certain extent. Electroacupuncture can improve the microcirculation, cerebral blood supply and the recovery of rat cranial nerve.
摘要:Objective To observe the curative effect of the therapies integrated Chinese and western medicine on infertility induced by oviducal obstruction. Method The therapies integrated Chinese and western medicine were given to 68 cases of infertility induced by oviducal obstruction, The administration of gentamicin, dexamethasone and chymotrypsin combined with Tiaohongsiwu Decoction orally and hydrotubation with normal saline. Result There were 42 cases cured (61.77 %), among them 32 cases with first grade and I degree of oviducal obstruction, 17 of pregnancy, and 19 relieved (27.94 %). The total effective rate was 89.71 %. Conclusion The therapies integrated Chinese and western medicine is effective in clinical practice and applied to the grass-roots hospitals.
摘要:Objective To investigate the curative effect of Wulingzhi Pills on keloid. Method The treatment group (n=54) was treated with Wulingzhi Pills and the control group (n=55) was treated with local blocking by corticosteroid. The results in two groups were compared. Result The excellent curative effective rate was 88.89 % in the treatment group and that in the control group was 90.91 %. The outcome of χ2 test showed that χ2=1.004, P<0.05. There was no significant difference between two groups. Conclusion Wulingzhi Pills can be administrated for the patients with keloid, especially for those with contraindication to hormones.
关键词:Wulingzhi Pills;keloid;activating blood circulation, removing blood stasis and relieving pain