摘要:Objective To investigate the pathogenesis of experimental chronic atrophic gastritis (CAG) accompanied by dysplasia (Dys) and therapeutic mechanism of Xiaopi Granules on the bases of microvessel formation of gastric mucosa and the changes of vascular endothelial growth factor (VEGF) and basic fibroblast grow factor (bFGF). Methods The rats were randomly divided into 5 groups. The model of CAG accompanied by Dys was established by using a synthetic method. The microvessel of gastric mucosa was displayed by antigen-antibody related to factor Ⅷ in immunohistochemistry method, and the expressions of VEGF and bFGF were displayed by immunohistochemistry method. Results The microvessel count (MVC), the positive expressions of VEGF and bFGF in the model group was increased than those in the normal group, while decreased in the Xiaopi Granules group with a significant difference compared with those of the model group. The curative effect of the Xiaopi Granules group was better than that of the natural recovery group and Weimeisu group. Conclusion The therapeutic effect of Xiaopi Granules on CAG accompanied by Dys may be related to that it can inhibit VEGF and microvessel formation.
摘要:Objective To observe the curative effect of the therapy of activating blood and removing stasis on sudden deafness, and to discuss the mechanism. Method The patients (n=60) were divided into 2 groups. The treatment group (n=30) was given Erlong Mixture orally and Danshen Injection by intravenous drip and the control group (n=30), Danshen Injection only. The curative effects of two groups were compared taking the symptoms, test of pure tone and acoustic impedance as the main observing indexes by using generally accepted standard for effect evaluation. Result The cure plus effectual rate and total effective rate were 63.33 % and 76.67 % respectively in the treatment group, and 53.33 % and 66.67 % in the control group. There was no significant difference between two groups (P>0.05) by Ridit analysis. In the treatment group the changes of tongue texture was significant (P<0.001). Conclusion The therapy of activating blood and removing stasis has a reliable curative effect on sudden deafness.
关键词:sudden deafness;activating blood and removing stasis;clinical study
摘要:Objective To investigate the curative effect of Breviscapine Injection on vertebrobasilar insufficiency and compare the changes of Transcranial Doppler (TCD) before and after the treatment. Method The patients with vertebrobasilar insufficiency (n=160) were randomly divided into 2 groups: Breviscapine Injection group (n=80) and Low-molecular-weight Dextran Injection group (n=80). The curative effects and the changes of TCD were compared before and after the treatment. Result Breviscapine Injection relieved the symptoms remarkably, such as dizziness and vomit in patients. The total effective rate was 97.50 % in Breviscapine Injection group, which was significantly higher than 83.75 % in Low-molecular-weight Dextran Injection group (P<0.05). The result of TCD showed that Breviscapine Injection group had a better outcome in blood flow rate of vertebrobasilar system than the control group (P<0.01) after the treatment. Conclusion Breviscapine Injection can treat effectively the vertebrobasilar insufficiency.
摘要:Objective To observe the curative effect of Shensongyangxin Capsules on palpitation with ventricular premature beat (VPB, TCM pattern of heart-blood deficiency and heart-collateral obstruction). Method The patients (n=80) with palpitation with VPB of TCM pattern of heart-blood deficiency and heart-collateral obstruction were randomly divided into the treatment group and control group (each n=40). The treatment group was treated with Shensongyangxin Capsules (4 capsules once and three times daily) and the control group was treated with Xinluping Tablets (150 mg once and three times daily) for 4 weeks as a treatment course. The tests of ECG in 24 hours,routine examination of blood,urine and stool,and the function examinations of the liver and kidney were given respectively before and after the treatment. Result The total effective rate of TCM symptoms was 92.5 % in the treatment group and 25.0 % in the control group. The outcome of the treatment group was better than that of the control group (P<0.05). Conclusion Shensongyangxin Capsules can treat palpitation with VPB (TCM pattern of heart-blood deficiency and heart-collateral obstruction) with a good curative effect.
摘要:Objective To observe the curative effect of TCM therapy of removing wind and replenishing qi and yin on child cough variant asthma (CVA) and discuss TCM etiology and pathogenesis of CVA. Method All 90 child patients were randomly divided into 3 groups (each n=30). The treatment group was given Qufengzhike Decoction and Yangyinyiqi Mixture orally, the control group 1, Qufengzhike Decoction only and control group 2, Meptin (Western medicine) and Yangyinyiqi Mixture. After two months the curative effect was observed. Result There was a significant difference among 3 groups (P<0.05). The curative effect of the treatment group was much better than that of the control group 1 (P<0.05) and control group 2 (P<0.01). Conclusion The therapy of removing wind and replenishing qi and yin has a good curative effect on child cough variant asthma.
关键词:child cough variant asthma;removing wind to stop cough;replenishing qi and yin;treating the incidental and fundamental simultaneoulsy
摘要:Objective To observe the curative effect of Zhuyeshigao Decoction combined with external application of Chinese medicine on child aphtha. Method Zhuyeshigao Decoction was given to 35 children and 1 % of procaine (2 mL) mixed with Xilei Powder and thick tea water for external application (3 times daily). Result After the treatment there were 2 cases cured within 3 days, 33 relieved within 3 days and cured within 7 days. Conclusion Zhuyeshigao Decoction combined with external application of Chinese medicine has a significant effect on child aphtha.
摘要:Objective To get know the research situation of diagnostic and therapeutic guide of Chinese and Western medicine in China and abroad, and to provide a thinking for setting up the clinical guide of Chinese medicine. Method The development program, method and content of clinical guide were analyzed and compared from recent materials through some network system, such as PubMed, CNKI and CMB, taking coronary heart disease (CHD) as an example, and the research orientation of the clinical guide of Chinese medicine was studied. Result The set-up of the clinical guide of Chinese medicine could not apply mechanically the international current model of evidence-based medicine (EBM), but the method should follow international practice for world approval. Conclusion Chinese medicine should use the method of EBM for reference to set up the evidence-evaluation system itself, which accords to its theoretical characteristics and clinical practice. On this base the clinical guide of Chinese medicine will be set up approved by international colleagues and been in keeping with the Chinese medical theory.
关键词:clinical guide;evidence-based medicine;theoretical characteristics;evaluation system
摘要:Objective To observe the curative effect of back open picking therapy and encircled needling on acne vulgaris, and discuss the mechanism. Method The patients with acne vulgaris were chosen and randomly divided into the treatment group treated with the back open picking therapy and encircled needling and the control group treated with routine acupuncture. The curative effects of two groups were compared and estimated according to the relief of clinical symptoms. Result The back open picking therapy and encircled needling relieved obviously the symptoms of the patients and the comparison between two groups was significant (P<0.05). Conclusion The back open picking therapy and encircled needling is an effective therapy for treating acne vulgaris with a higher cure rate and good curative effect.