最新刊期
期 1 ， 2008
- 摘要：Objective To evaluate the efficacy and safety of safflor yellow for injection to cerebral infarction in acute stage. Method The placebo （random, blind and basic treatment） was used as the control experiment. The patients were randomly divided into the treatment group （n=77） and control group （n=26）. Two groups were all treated with the basic medicines, i.e. troxerutin injection （200 mg） by intravenous drop once daily. Besides safflor yellow for injection （80 mg） was given to the treatment group by intravenous drop once daily and placebo was given to the control group. One treatment course was for 14 days. Result The scores of stroke and neurological impairment were decreased in two groups respectively 7 or 14 days after the treatment, and were more significant along with time. The improvement rates of the total scores in two groups had a statistic significance （P<0.01）. Before the treatment the baseline score had an influence on the curative effect evaluation, while after the influence was subtracted the improvement rates of the total scores in two groups still had a statistic significance 7 or 14 days after the treatment （P<0.01）. The comparison of bad events incidence in 2 groups had no statistic significance （P>0.05）. Conclusion Safflor yellow for injection is safe and effective for treating cerebral infarction in acute stage. It can relieve the symptoms efficiently and improve living ability of the patients.关键词：safflor yellow;cerebral infarction;acute stage
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发布时间：2021-09-15 - 摘要：Objective To observe the curative effect of Yiqihuoxue Compound Formula combined with Western medicines on the complications and restenosis after percutaneous transluminal coronary angioplasty （PTCA）. Methods The patients with coronary heart disease after PTCA （n=40） were randomly divided into the treatment group and control group （each n=20）. The control group was treated with routine Western medicines and the treatment group was treated with Yiqihuoxue Compound Formula besides the routine Western medicines. The treatment course was for 3 months and then the follow-up visits were given to the patients for 6 months. The symptoms, electrocardiogram outcomes, incidence rate of angina, hemorrheological indexes and incidence rate of restenosis were observed. Results In relief of symptoms, improvement of myocardial ischemia, decrease of incidence rate of angina and descent of incidence rate of restenosis the comparison between the treatment group and control group was different significantly （P<0.05）. Conclusion Yiqihuoxue Compound Formula can improve the curative effect on the complications after PTCA and prevent the restenosis.关键词：percutaneous transluminal coronary angioplasty;Yiqihuoxue Compound Formula;curative effect;restenosis
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发布时间：2021-09-15 - 摘要：Objective To investigate the changes of WBC platelet agglomeration in stroke in acute seizure phase and the correlation between these changes and TCM syndromes. Methods WBC platelet agglomeration was detected respectively whin 1 week and on the 14th day after stroke invasion, and at the same time the patients were evaluated with TCM syndrome scores. The descriptive statistics and different test were given to the patients at two time points and the research was conducted on the correlation between WBC platelet agglomeration at two time points and TCM syndromes. Results In male patients there was a statistic difference in WBC platelet agglomeration within 1 week and on the 14th day （P<0.05）. Within 1 week there was a statistic difference in WBC platelet agglomeration between male and female patients （P<0.05）. WBC platelet agglomeration was correlated to the syndrome of fire-heat within 1 week （P<0.05）. There was a statistical difference between the patients suffered from the fire-heat syndrome and those did not suffer from the fire-heat syndrome（P<0.05）. The differences of WBC platelet agglomeration within 1 week and on the 14th day were correlated to the difference of the score value of the fire-heat syndrome （P<0.05）. Conclusion Within 1 week after stroke invasion WBC platelet agglomeration mostly was normal or inhibited, which was inhibited more in male than in female patients, and more in the patients suffered from the fire-heat syndrome. On the 14th day the more the fire-heat syndrome changed, the less the WBC platelet agglomeration changed.关键词：WBC platelet agglomeration;stroke in acute seizure phase;syndromes;correlation
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发布时间：2021-09-15 - 摘要：Objective To discuss the distribution characteristics of TCM syndromes in depressive insomnia. Methods The survey of TCM syndromes and questionnaire of PSQI were given to 112 patients with depressive insomnia. Results The proportion of premature-awake patients was 73.21 % in all insomnia patients, that of the patients with diurnal residual effects （serious in the morning） was 79.46 %, and that of the patients with the syndrome of heart and spleen deficiency was 55.36 %, which was the most common syndrome type. The correlation analysis related to PSQI factors showed that the patients with the syndrome of heart and spleen deficiency had the shortest time of falling asleep and sleep time, and the most remarkable diurnal residual effects. Conclusion The depressive insomnia is mostly related to TCM syndrome of heart and spleen deficiency with the clinical characteristics of premature-awake and diurnal residual effects （serious in the morning）.关键词：depressive insomnia;clinical characteristics;TCM syndromes;heart and spleen deficiency
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发布时间：2021-09-15 - 摘要：Objective To observe the inhibitory effect of Xinjialiangfu Formula on transplantation human gastric cancer. Methods After culturing and propagating BGC-823 of human gastric cancer was implanted to BALB/C-nu mice to establish the tumor model, which then was treated interferingly with 5-fluorouracil （5-FU） and different doses of Xinjialiangfu Formula. The inhibitory effect of Xinjialiangfu Formula on BGC-823 was evaluated by the tumor inhibitory rate. Results The tumor inhibitory rates of 5-FU group and different-dose Xinjialiangfu Formula groups were respectively 54.2 %, 54.3 %, 36.8 % and 23.3 %. The comparison between the model group and 5-FU group or high-dose Xinjialiangfu Formula group in tumor weight was significant statistically （P<0.05）. Conclusion High-dose of Xinjialiangfu Formula has a significant inhibitory effect on BGC-823 of human gastric cancer.关键词：Xinjialiangfu Formula;cell line of human gastric cancer;tumor inhibitory rate
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发布时间：2021-09-15 - 摘要：Objective To investigate the antitumor effect and immunological regulation of ginsenoside Rh2 and ginsenoside Rg3 from Panax notoginseng through detecting the activities of tumor necrotic factor-α （TNF-α） and interleukin-2 （IL-2） in peripheral blood of mice with melanoma-B16. Methods After melanoma-B16 was transplanted the mice were randomly divided into 9 groups, including the Rh2 groups and Rg3 groups with different doses of ginsenoside Rh2 and ginsenoside Rg3 respectively, group combined Rh2 and Rg3, CTX group and model group. The tumor-inhibitory rate, thymus and spleen indexes were calculated. The contents of serum TNF-α and IL-2 were detected by radioimmunoassay. Results There were some tumor-inhibitory effects in the Rh2 groups and Rg3 groups. The tumor-inhibitory rate in the high-dose and medium-dose Rh2 groups, high-dose Rg3 group and group combined Rh2 and Rg3 was respectively 35.5 %, 30.1 %, 33.6 % and 38.6 %. It was significant statistically （P<0.05）in tumor weight in above groups compared with that of the model group. Comparing to the CTX group ginsenoside Rh2 or ginsenoside Rg3 used separately or jointly, especially combined administration, all increased the contents of serum TNF-α and IL-2 as well as immune organ weight of mice with B16. Conclusion Ginsenoside Rh2 and ginsenoside Rg3 from Panax notoginseng has effects of inhibiting melanoma-B16, and improving immune function in mice. The combined administration of ginsenoside Rh2 and ginsenoside Rg3 is more efficacious.
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发布时间：2021-09-15 - 摘要：Objective To observe the occur and symptomatological characteristics of the syndrome of damp-heat in Middle Jiao in old patients with lung infection. Method The syndrome differentiation and analysis were given to 152 old patients as well as yang and middle-aged patients with lung infection. The occur and symptomatological characteristics of lung infection with syndrome of damp-heat in Middle Jiao were summed up. Result In old patients with lung infection the proportion of patients complicated by the syndrome of damp-heat in Middle Jiao was 49.3 %, which was obviously higher than that in yang and middle-aged patients. The symptomatological characteristics mostly included bitterness and sticky in the mouth, no desire to drink, poor appetite, abdominal distention, red tongue body and greasy tongue coating, and also heaviness feeling in the head and body and viscous stool. Conclusion The old patients with lung infection often suffer from the syndrome of damp-heat in Middle Jiao with a higher occurrence rate, which indicates that the syndrome is significant in clinic.关键词：lung infection in old patients;syndromes of TCM;syndrome of damp-heat in Middle Jiao
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发布时间：2021-09-15 - 摘要：<正>2005年北京中医药大学开始实施"中青年名中医"工程。该工程旨在培养一批优秀的中青年中医临床人才,通过为他们创造条件、搭建平台,使其尽快成为热爱中医事业、医德高尚的,具有广博深厚的中医理论功底、精湛的医疗技能和丰富临证经验关键词：名老中医;师承;中医临床
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发布时间：2021-09-15 - 摘要：Objective To evaluate systematically the curative effect and adverse reactions of Xiaoqinglong Decoction in treatment of asthma. Methods After searching the related database of China and other countries systematically, the randomized control trials （RCT） related to the treatment of asthma with Xiaoqinglong Decoction, dummy and Western medicines were identified and adopted. The evaluative standard recognized generally was applied to appraise the quality of adopted RCT , including randomization, distribution concealment blindness, leaving and missing visit. Then the curative effect of Xiaoqinglong Decoction on asthma was analyzed systematically and synthetically. Results There were 26 pieces of literature on RCT （related to 2 028 patients） accorded with the adoptive standard, but their methodology quality was lower. In the adoptive RCT literature there was no one about the study on the comparison between Xiaoqinglong Decoction and dummy. The results indicated that Xiaoqinglong Decoction combined with Western medicines had a remarkable preponderance in terms of controlling asthma and promoting the lung functions. In contrast with relief symptoms with Western medicines Xiaoqinglong Decoction was superior to Western therapies only in the promotion of the lung functions. There were no serious adverse reactions reported in all adoptive RCT. Conclusion The evidence of medium-level on hand shows that Xiaoqinglong Decoction is efficacious for controlling asthma symptoms and promoting the lung functions. The quality of methodology and report of small sample of RCT, however, is lower, and the curative effect of Xiaoqinglong Decoction needs to be approved further by strict designed clinical trials with large sample.关键词：Xiaoqinglong Decoction;asthma;randomly control trials;systematically evaluation;methodology evaluation
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发布时间：2021-09-15 - 摘要：<正>腹腔镜胆囊切除术（Laparoscopic Cholecystectomy,LC）是目前胆囊切除的首选术式。与传统开腹胆囊切除术（Open Cholecystectomy,OC）相比,两者都存在着静脉血栓栓塞性疾病（venous thromboembolism,VTE）形关键词：腹腔镜胆囊切除术;行气活血汤;静脉血栓栓塞性疾病;预防
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发布时间：2021-09-15 - 摘要：<正>落枕是颈部常见的筋伤之一,又称为失枕。多因睡眠姿势不良或感受风寒后所致,表现为一侧颈部出现疼痛、酸胀,可向上肢或背部放射,活动不关键词：落枕;平衡针;强刺激推拿
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发布时间：2021-09-15 - 摘要：<正>帕金森病（Parkinson’s Disease,PD）又名震颤麻痹,是常见于中老年人的神经系统的退行性疾病,临床主要表现为静止性震颤、肌张力增高、运动迟缓、姿势反射障碍及自主神经功能紊乱等症状。以选择性中脑黑质多巴胺神经元丧失、纹状体多巴胺含量显著减少以及黑质和蓝斑存在Lewy小体为关键词：帕金森病;中医药;经典文献
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发布时间：2021-09-15 - 摘要：<正>形与神,是人体生命活动过程中最基本的两个方面。中医学认为,形、神二者之间有着密不可分的联系。临床治疗时,通过调形可以治神,通过调神亦可以治形。历代中医古籍文献不乏相关记载。如明·周于蕃《仙传男女小儿科推拿秘诀》采用按摩鱼肚关键词：形神关系;形神疾病;发病特点;治疗
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发布时间：2021-09-15 - 摘要：<正>血脂异常是导致动脉粥样硬化的主要危险因素之一,由此引起的心脑血管疾病严重危害人类健康。如何寻找有效药物治疗血脂异常成为当今研究心脑血管疾病的重要课题。通过对中医药的研究,寻找出安全、可靠、有效的调脂疗法和药物非常重关键词：血脂异常;病因病机;辨证;辨病;中医药疗法
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发布时间：2021-09-15 - 摘要：<正>早泄是男科常见的难治病,成年男子的发病率为35%～50%,是指男子在性交时失去控制射精的能力,阴茎插入阴道之前或刚插入即射精,或女性在性交中达到性高潮的频度不足于50%[1]。中医认关键词：早泄;清肝利湿;疏肝解郁;滋阴柔肝
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发布时间：2021-09-15 - 摘要：<正>中西医结合治疗疾病已是很多中医同道普遍接受并实践、且被越来越多的西医同道开始接受并采纳的方法。本文总结了10余年来笔者治疗老年肺炎的经验,重点剖析中西医认识老年肺炎的不同角度、中医病机病证的特点,并以此为依据,对中西医结合治疗老年肺炎进行探讨。关键词：老年肺炎;中医;西医
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发布时间：2021-09-15
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