摘要:Objective To investigate the correlation between hypertension and osteoporosis and to discuss the interrelationship between the syndrome types of hypertension and osteoporosis by using Chinese medical theory.Method There were 103 cases of hypertension and 135 cases with normal blood pressure(NBP).The cases of hypertension were divided into 5 groups according to the syndrome types differentiated by Chinese medicine,and then the groups were given the detections of bone mineral density(BMD) respectively in the lumbar,collum femoris,Wards triangular area and Greater trochanter of femur.Among all cases 105 cases(82 cases of hypertension and 23 cases with NBP were given the determination tests of bone alkaline phosphatase(BALP),bone gla protein(BGP) N-telopeptide of type I collagen(NTX) and insulin-like growth factor 1(IGF-1).The indexes of BMD and bone metabolism in different groups were compared.Result The BMD indexes of Wards triangular area in the hypertension groups were obviously lower than those in the NBP group(P<0.05).In the cases of hypertension those with the syndrome of dual deficiency of yin and yang had much lower BMD indexes in the collum femoris,Wards triangular area and Greater trochanter of femur than those with the syndrome of ascendant hyperactivity of liver yang.The BMD indexes in the collum femoris had a great significance(P<0.01).The indexes of BALP and IGF-1 in the cases with the syndromes of dual deficiency of yin and yang and abundant accumulation of phlegm-dampness were much lower than those in the cases with the syndrome of ascendant hyperactivity of liver yang.Conclusion BMD index is decreased in hypertension patient,which more significant in the type of yin-yang deficiency.Hypertension and the syndromes of dual deficiency of yin and yang have the same pathogenesis,i.e.deficiency of kidney essence.
摘要:Objective To observe the curative effect of Qianlie Granules on the contraction lesion of musculi detrusor vesicae induced by benign prostatic hyperplasia(BPH).Method The patients with the contraction lesion of musculi detrusor vesicae(n=45) were randomly divided into the treatment group(n=30,treated with Qianlie Granules) and the control group(n=15,treated with Tongniaoling Tablets).After 8 weeks the changes of the results of International Prostatic Symptom Score(I-PSS),influence of miction on the quality of life(QoL),residual urine volume(RUV) and urodynamics were observed.Result After treatment for 8 weeks,the changes of the results of I-PSS were obviously decreased in two groups(P<0.05,P<0.01),which were more significant in the treatment group than in the control group(P<0.01).In the treatment group the difference of QoL change before and after the treatment was significant(P<0.01),and the improving rate of contraction of musculi detrusor vesicae was 73.3 %,the total effective rate was 76.7 % and the effectual rate was 33.3 %.The outcomes of the treatment group were all better than those of the control group(P<0.05,P<0.01).Conclusion Qianlie Granules has a better curative effect on the contraction lesion of musculi detrusor vesicae induced by BPH.
关键词:Qianlie Granules;benign prostatic hyperplasia;contraction of musculi detrusor vesicae
WAN Ming-cai1,FENG Feng1,WANG Xin-wei1,ZHU Tai-yong2,HUANG Man-yu2,BI Jun-hua2
Vol. 0, Issue 2, Pages: 10-12(2008)
摘要:Objective To observe the influence of Shengji Solution combined with vacuum-assisted closure(VAC) on wound healing in experimental animals.Method All 100 SD rats were randomly divided into the model group,benne oil group,Shengji Solution group,VAC group and combined group,and all groups were treated with relevant therapies respectively.The healing time and macrophage number changes in wound were observed.Result The healing time in the combined group and VAC group were much shorter than those in other groups(P<0.05).In the Shengji Solution group the macrophage number in wound were higher than those in the combined group and VAC group on the 3rd,6th and 9th day and after the healing.In the combined group the macrophage number in wound were higher than those in the VAC group on the 9th day and after the healing(P<0.05).Conclusion Shengji Solution combined with VAC can improve wound healing significantly,and one of the important mechanisms may be related to a higher expression of macrophage in wound.
摘要:Objective To study the curative effect of acupuncture on depression through applying the prognosing method of artificial neural network(ANN).Method The curative effect was prognosed by using ANN method based on clinical studies.The attention was paid to the therapeutical factors and pathological indexes,which closely related to the curative effect of acupuncture on depression.These factors and indexes were chosen as ANN input variables and the outcomes of scales after the treatment as the output variables.The collected cases were divided into the training samples and testing samples of ANN,and their clinical application were discussed.Result There was no significant difference in the total curative effects between two groups.The predictive rates of ANN methods to the scores from HAMD and SDS scales were respectively 79.03 % and 73.93 %.Conclusion The application of ANN method is one of valuable research objects in the clinical study of acupuncture science.
摘要:Objective To study the effect of tea polyphenols(TP) on the proliferation of human umbilical vein endothelial cells(HUVEC) in vitro by the variance analysis of factorial design.Methods The effects of TP on the proliferation of HUVEC were detected by two-factor 3×5 factorial design and methyl thiazolyl tetrazolium(MTT) assay in different concentrations and different time periods.The morphological changes of HUVEC were observed by using the inverted phase contrast microscope.Results In 24-hour period the groups with TP concentrations of 120,160 and 240 mg/L,and in 48-hour and 72-hour periods the groups with TP concentrations of 80,120,160 and 240 mg/L had significantly different OD values compared with those of the control group.The values of IC50 were 184.41,127.70 and 108.98 mg/L on 24th,48th and 72nd hour respectively.There was an interaction between effective period and concentration of TP.Conclusion Tea polyphenols can inhibit the proliferation of HUVEC in vitro,and there is a dependent relationship of dose-effect to time-effect.
摘要:Objective To discuss the curative effect of pricking and cupping therapy on zona.Method The patients with zona(n=78) were randomly divided into two groups.The treatment group(n=40) was treated with pricking and cupping therapy combined with TDP irradiation and the control group(n=38) was treated with Zovirax Tablets combined with encircled pricking along zona edge and local TDP irradiation.Result The total effective rate was 100.0 % in the treatment group and 86.8 % in the control group.The difference between two groups was significant(P<0.05).Conclusion Pricking and cupping therapy combined with TDP irradiation has a good curative effect on zona with a shorter treatment course and higher cure rate.
关键词:zona;local pricking;pricking and cupping therapy;TDP irradiation
摘要:Objective To observe the influence of Bushenquyu Decoction on serum levels of endothelin(ET),nitrous oxide(NO) and activated protein C resistance(APCR) in the cases of thrombotic diseases.Method The patients with thrombotic diseases(n=60) were randomly divided into the treatment group and control group(each n=30).The patients in two groups in acute seizure phase were treated with enteric aspirin suppository,besides the treatment group was given Bushenquyu Decoction orally and the control group was given urokinase by intravenous drip.The changes of above indexes were compared between two groups before and after the treatment.Result After the treatment the levels of ET and APCR decreased all in two groups(P<0.05) and NO level increased all in two groups(P<0.05).It is significant statistically in the comparison between two groups(P<0.05).Conclusion Bushenquyu Decoction can decrease the levels of ET and APCR,and increase NO level in the treatment of thrombotic diseases.
关键词:Bushenquyu Decoction;thrombotic diseases;endothelin;nitrous oxide;activated protein C resistance
摘要:Objective To observe the curative effect of electroacupuncture in Neiguan(PC6) and Jianli(RN11) on depression.Method The patients with hypodepression and subdepression(n=46) were chosen from the out-patient department and wards,and treated with electroacupuncture in Neiguan(PC6) and Jianli(RN11).Result The results of own control showed that the scores of Hamilton’s depression scale(HAMD) were different significantly(P<0.05) before and after the treament.The total effective rate was 88.1 %.Conclusion Electroacupuncture in Neiguan(PC6) and Jianli(RN11) for treating depression has a curative effect and is safe.
关键词:depression;electroacupuncture;pair of acupoints in ancient prescription;Neiguan(PC6);Jianli(RN11);Hamilton’s depression scale