最新刊期
      期 5 ， 2009
      • XUE Yu-xian1,GAO Jian-feng2,LIU Ke3
        Vol. 16, Issue 5, Pages: 1-5(2009)
        摘要：Objective To find out the protective mechanism of electroacupuncture in senile cerebral ischemia and reperfusion（I/R） lesion based on the proliferation and differentiation of endogenous neural stem cells in dentate gyrus（DG）.Methods The rat model of cerebral ischemia was established by using the method of middle cerebral artery occlusion（MCAO）.All rats were divided into the sham-operation group,model group,non-acupoint treatment group and acupoint treatment group.The immunohistochemistry assay was applied to detect the positive neuron count of bromodeoxyuridine（BrdU）,neuronal nuclei,（NeuN） and glial fibrillary acid protein（GFAP） in DG.The changes of cerebral pathology,water content,integrals of neural symptoms,and cell proliferation and differentiation in DG were observed at different time points,i.e.cerebral ischemia for 3 hours,and reperfusion for 1,3,7 and 12 days respectively.Results In the model group the cerebral water content（at all time points）,integrals of neural symptoms（at all time points）,BrdU positive neurons（at all time points）,BrdU/NeuN doubly labeled positive neurons（I/R for 3,7 and 12 d） and BrdU/ GFAP doubly labeled positive neurons（I/R for 7 and 12 d） were higher than those in the sham-operation group.There was no significant difference in all indexes between the model group and non-acupoint treatment group at all time points.In the acupoint treatment group the cerebral water content（I/R for 1,3 and 7 d）,integrals of neural symptoms（I/R for 3,7 and 12 d） and BrdU/GFAP doubly labeled positive neurons（I/R for 7 and 12 d） were lower than those in the model group and non-acupoint treatment group,and BrdU positive neurons（at all time points） and BrdU/NeuN doubly labeled positive neurons（at all time points） were higher than those in the model group and non-acupoint treatment group.Conclusion The proliferation and differentiation of endogenous neural stem cells in DG can be stimulated by cerebral ischemia.The mechanism of electroacupuncture in acupoints against cerebral ischemia and reperfusion lesion may be related to that electroacupuncture can improve the proliferation and differentiation of endogenous neural stem cells in DG.  
        关键词：electroacupuncture;senile;cerebral ischemia and reperfusion;neural stem cells;proliferation;differentiation;rats   
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      • Vol. 16, Issue 5, Pages: 2(2009)
        摘要：<正>《北京中医药大学学报（中医临床版）》是由教育部主管、北京中医药大学主办的中央级高级中医药学术期刊。主编为中国中医界学术权威王永炎院士。办刊宗旨是继承弘扬中国传统医药文化,宣传中医药临床应  
          
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      • Vol. 16, Issue 5, Pages: 5(2009)
        摘要：<正>本刊是由国家教育部主管、北京中医药大学主办的中医药学术期刊。主编为中国中医界学术权威王永炎院士。主要面向国内外中医药医学院校的师生,各级各类医院的临床医生等。设中医临床基础研究、临床  
          
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      • LI Zhi-gang1,YANG Jin-xiang1,ZHANG Wei2,XIE Chun-guang3,DUAN Qu3,Director:WANG Zai-mo3
        Vol. 16, Issue 5, Pages: 6-9(2009)
        摘要：Objective To study the influences of Ganxinning Decoction on protein expressions of α-smooth muscle actin（α-SMA）,matrix metalloproteinase-13（MMP-13） and tissue inhibitor of metalloproteinase-1（TIMP-1） of liver tissue in rats with hepatic fibrosis.Method All male SD rats（n=68） were randomly divided into the normal group,model group,colchicines group,high-dose Ganxinning Decoction group and low-dose Ganxinning Decoction group.The rat model of hepatic fibrosis was established by the hypodermic injection of carbon tetrachloride（CCl4） and feeding by high-fat low-protein feed and 30% alcohol.At the end of the 6th week the expressions of α-SMA,MMP-13 and TIMP-1 were detected by using immunohistochemical stain method.Result The expressions of α -SMA and TIMP -1 decreased significantly in high -dose Ganxinning Decoction group,low -dose Ganxinning Decoction group and colchicines group compared with those in the model group（P<0.05）.The expressions of α-SMA and TIMP-1 decreased significantly in high-dose Ganxinning Decoction group and low-dose Ganxinning Decoction group compared with those in colchicines group（P<0.05）.The expression of MMP-13 in high-dose Ganxinning Decoction group,low-dose Ganxinning Decoction group and colchicines group increased significantly compared with that in the model group（P<0.05）.The expression of MMP-13 in high -dose Ganxinning Decoction group and low -dose Ganxinning Decoction group increased significantly compared with that in colchicines group（P<0.05）.Conclusion The inhibitory effect of Ganxinning Decoction on hepatic fibrosis may be related to that it can reduce the protein expressions of α-SMA and TIMP-1,and promote MMP-13 expression.  
        关键词：Ganxinning Decoction;hepatic fibrosis;α-smooth muscle actin;matrix metalloproteinase-13;tissue inhibitor of metalloproteinase-1;rats   
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        发布时间：2021-05-20
      • CHANG Li-jing1,LIANG Rong1,WANG Zhao-ping2,GAO Si-yan1,A’NAN Etsuko1,WANG Sheng-hua2
        Vol. 16, Issue 5, Pages: 9-11(2009)
        摘要：Objective To analyze common pulse manifestations and characteristics of hysteromyoma.Method The teaching materials of Chinese gynecology for TCM higher education（edition 4th,5th,6th and 7th）,125 documents about pulse manifestations of hysteromyoma from medical journals from 1999 to 2008,and the medical records of modern famous TCM physicians about pulse manifestations from more than 4000 cases of hysteromyoma were analyzed.Result The specificity and regularity of the pulse manifestations of hysteromyoma were summarized.The occurrence rate of the pulse of deep and wiry was the highest among 32 pulse manifestations recorded in clinical practice.Conclusion The pulse manifestations of hysteromyoma are characterized by deep pulse in the pulse position,and wiry pulse,stagnant pulse and thready in the pulse shape and force.  
        关键词：hysteromyoma;pulse diagnosis;deep pulse;wiry pulse;syndrome differentiation of Chinese medicine   
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      • WU Hong-dong1,WANG Qi1,DONG Jing2
        Vol. 16, Issue 5, Pages: 12-13(2009)
        摘要：Objective To discuss the pathogenic factors of hypertension on the base of TCM constitution science.Method The multiple Logistic regression analysis was carried out in hypertension patients in the case group（n=271） and those without hypertension in the control group（n=302） by applying case-control study of clinical epidemiology.The correlative degree between relevant constitutional factors and hypertension was explored.Result There were 3 constitutional factors enclosed in the regression equation,including mild constitution,phlegm-damp constitution and blood-stasis constitution.The partial regression coefficients were -0.602,1.437 and 0.592 respectively.Conclusion The risk factors of hypertension include phlegm-damp constitution and blood-stasis constitution.The phlegm-damp constitution is more important in the onset of hypertension and mild constitution is a protective factor.  
        关键词：hypertension;constitution;Logistic regression analysis   
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        发布时间：2021-05-20
      • SUN Wei-wei1,LIU Zhong-jie1,ZHANG En2,HUO Yan-hong3,GUO Ying-bo4,JIAO Jian-peng5,LIU Shang-jian1,Director:WANG Yao-xian1
        Vol. 16, Issue 5, Pages: 14-16(2009)
        摘要：Objective To observe the distribution of TCM symptoms of chronic kidney disease（CKD） in the third,fourth and fifth stage.Method The distributions of the syndrome of healthy-qi deficiency,syndrome of tip excess and syndrome of healthy-qi deficiency complicated with tip excess were observed,according to TCM syndrome differentiation and classification,in 290 patients with CKD in the third,fourth and fifth stage.Result The occurrence rate of spleen-kidney qi deficiency was the highest in the syndrome of healthy-qi deficiency,and that of dampness heat was highest in the syndrome of tip excess in the third stage of CKD.The occurrence rate of spleen-kidney yang deficiency was the highest in the syndrome of healthy-qi deficiency,and that of dampness turbidity was the highest in the syndrome of tip excess in the fourth and fifth stage of CKD.Conclusion The syndrome of healthy-qi deficiency of CKD in the third,fourth and fifth stage develops from spleen-kidney qi deficiency to spleen-kidney yang deficiency.The syndrome of tip excess includes mainly dampness heat,dampness turbidity and blood stasis.  
        关键词：chronic kidney disease;TCM syndromes;spleen-kidney qi deficiency;spleen-kidney yang deficiency;dampness heat;dampness turbidity;blood stasis   
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        发布时间：2021-05-20
      • GUO Rong-juan1,WANG Jia-lin2,XING Jia1,ZHANG Yun-ling1,SUN Yu-shuang2,YU Miao2
        Vol. 16, Issue 5, Pages: 17-19(2009)
        摘要：Objective To discuss the characteristics of TCM syndrome differentiation factors and dysmnesia in the patients with insomnia accompanied by dysmnesia from outpatient department of neurology in a general hospital.Method The patients with insomnia accompanied by dysmnesia and those without dysmnesia were divided into two groups（each n=50） and the difference of TCM syndrome differentiation factors was compared between two groups.Result There was a greatly significant difference between two groups in directed memory,associative learning,image free memory,recognition of meaningless figure and portrait character associative retrieval（P<0.01）.The occurrence rate of blood-stasis syndrome was higher in the patients with insomnia accompanied by dysmnesia than in those without dysmnesia（P<0.05）.Conclusion The memory impairment of patient with insomnia involves directed memory,associative learning,image free memory,recognition of meaningless figure and portrait character associative retrieval.The insomnia accompanied by dysmnesia is related to blood stasis.  
        关键词：insomnia;dysmnesia;TCM syndrome differentiation factors;clinical memory scale   
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      • Vol. 16, Issue 5, Pages: 19(2009)
        摘要：<正>根据国家标准GB3358-82《统计学名词及符号》的有关规定,请作者书写统计学符号时注意以下规格:①样本的算术平均数用英文斜体小写x表示,不用正体X,也不用M或Mean（中位数仍用M）;②标准差用  
          
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      • CHANG Xue-hui1,ZHANG Liang-zhi2
        Vol. 16, Issue 5, Pages: 20-21(2009)
        摘要：Objective To observe the curative effect of Huoxuetongfu Formula on cerebral hemorrhage in acute phase.Method All patients with cerebral hemorrhage in acute phase（n=60） were randomly divided into the treatment group（n=30） and control group（n= 30）.The control group was treated with the synthesis therapy of Western medicine,and the treatment group was treated with selfmade Huoxuetongfu Formula based on the same treatment as the control group.A therapeutic course was 15 days.Result The total effective rate was 86.67% in the treatment group and 73.33% in the control group.There was a significant difference in the curative effect between two groups.The improvement of the neurological functional deficit score was much better in the treatment group than that in the control group.Conclusion Huoxuetongfu Formula accompanied by Western routine treatment has a reliable curative effect on cerebral hemorrhage in acute phase.  
        关键词：Huoxuetongfu Formula;cerebral hemorrhage;clinical curative effect   
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      • ZHANG Hong-tai1,WANG Zai-jian1,LIU Zhi-min2,FAN Ying-yi1
        Vol. 16, Issue 5, Pages: 22-23(2009)
        摘要：Objective To observe the curative effect of Modified Zuojinxianglian Decoction combined with the triple therapy on gastritis correlated to Helicobacter pylori（GHp）.Method All 100 patients were randomly divided into the treatment group（n=50） treated with Modified Zuojinxianglian Decoction combined with the triple therapy and control group（n=50） treated with the triple therapy only.The curative effect,relief of main symptoms and recurrence rate were observed in two groups.Result The comparison of the curative effect between tow groups was insiginificant statistically（P>0.05）.The relief of stomachache and ructus in the treatment group was more significant than that in the control group（P<0.05）.Conclusion The therapy integrated Chinese and Western medicine is effective in the treatment of GHp.  
        关键词：triple therapy;Modified Zuojinxianglian Decoction;gastritis correlated to Helicobacter pylori   
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      • Vol. 16, Issue 5, Pages: 24-25(2009)
        摘要：<正>口僻是以口眼（口呙）斜为主要症状的疾病。在历代文献中,多认为本病病机为感受风邪,或感风寒、风热之邪致阳明经络阻滞[1]。1中医症状学及证候特征辨析口僻以口眼（口呙）斜为特有症状,从症状及文献描  
        关键词：口僻;证候;病因病机   
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      • Vol. 16, Issue 5, Pages: 26-27(2009)
        摘要：<正>"六对论治"是吕仁和教授在长期的医疗实践中总结形成的,包括对症论治、对症辨证论治、对症辨病与辨证相结合论治、对病论治、对病辨证论治、对病分期辨证论治[1]。吕教授认为,疾病的发生发展  
        关键词：糖尿病周围神经病变;消渴病痹痿病;六对论治   
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      • Vol. 16, Issue 5, Pages: 28-29(2009)
        摘要：<正>许昕教授为首都医科大学附属北京中医医院妇科主任医师,硕士生导师,她在运用中医药治疗妇科疾病方面造诣颇深,疗效显著。现试将其治疗月经失调的学术理论观点及临床经验整理如下。  
        关键词：月经失调;病因病机;辨证论治   
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      • Vol. 16, Issue 5, Pages: 29-31(2009)
        摘要：<正>糖尿病是常见病、多发病。我国调查成人糖尿病患病率1979～1980年为1%;1994～1995年为2.5%;1995～1996年为3.21%[1]。其中2型糖尿病患者大多没有典型多饮、多食、多尿及形体消瘦的"三多一  
        关键词：消渴病;脾;痰湿;辨证;用药   
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      • Vol. 16, Issue 5, Pages: 32-33(2009)
        摘要：<正>方证关系是近年来用以研究和探讨中医辨证论治理论及其临床用药规律的重要命题之一,方证对应是核心问题,也是主要研究方法,理解方证对应的思想与内涵,对阐释方剂的配伍规律、作用机  
        关键词：方证对应;意义;研究思路   
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      • Vol. 16, Issue 5, Pages: 34-35(2009)
        摘要：<正>五脏应时是《内经》中认识脏腑病理生理的一个重要学术观点。五脏应时的核心是指人体内在脏腑的生理功能,能自发主动地调整自身以适应外界季节时辰变化,并与外界时辰季节变化具有同步的  
        关键词：心应夏;心血管系统疾病;五脏应时   
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      • Vol. 16, Issue 5, Pages: 35(2009)
        摘要：<正>近年来在《中医教育》《北京中医药大学学报》《北京中医药大学学报（中医临床版）》发表过文章并由于种种原因未领取稿费的作者及未领取审稿费者的审稿专家,请速来北京中医药  
          
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      • Vol. 16, Issue 5, Pages: 36-37(2009)
        摘要：<正>糖尿病性肾小球硬化症又称糖尿病肾病（diabetic nephropathy,DN）,是糖尿病最主要的微血管并发症之一。DN发病率在1型糖尿病中约为40%～50%,在2型糖尿病中约为20%～30%[1]1414。DN已经成为终末期肾衰竭的主要原因。糖尿病患者一旦  
        关键词：糖尿病肾病;中医;诊治   
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      • Vol. 16, Issue 5, Pages: 38-41(2009)
        摘要：<正>在中国中西两大派别的医疗体系相互补充、取长补短,共同担当着救死扶伤、康复保健的重任。而在北美（主要指美国和加拿大）,除了西医之外,尚存在着其他诸多的医学体系及治疗手段。西医被冠  
        关键词：补充医学;替代医学;北美医疗保健   
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      • Vol. 16, Issue 5, Pages: 42-44(2009)
        摘要：<正>功能失调性子宫出血（简称功血）,是指调节生殖的神经内分泌机制失常引起的异常子宫出血。西医认为机体受内部和外界各种因素诸如精神紧张、情绪变化、营养不良、代谢紊乱及环境、气候骤变等影响时,可通过大脑皮层和中枢神经系统引起下丘  
        关键词：傅青主女科;功血;中医治疗   
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      • Vol. 16, Issue 5, Pages: 44-46(2009)
        摘要：<正>系统性红斑狼疮（SLE）是一种严重的多系统受累的全身自身免疫性疾病。西医多采用激素、免疫抑制剂、血浆置换、造血干细胞移植及抗疟药治疗,虽有较好的近期疗效,但远期疗效欠佳,同时由于药物的毒副作用及继发感染等因素,限制了其对  
        关键词：系统性红斑狼疮;中医;进展   
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