摘要:The paper drew out the background of translational medicine and its internal relation with Chinese medicine, the direction needing to be adjusted and preventive and therapeutic strategies of Chinese medicine for community chronic diseases from the analysis on symbolic changes of clinical medicine research. The demands of community to TCM technology will be principal task, team construction with multi-disciplines, organic safeguard, and standardization of clinical research in community, precondition. The goal of clinical research is to benefit patients and diverse mode of prevention and treatment is future orientation.
摘要:Translational medicine is a new concept in internal and international scientific field,which is to promote a quick translation from basic research results to medical application and set up a two-way channel between basic research and clinical practice.The authors analyzed the characteristics,advantages and disadvantages of Chinese medicine through the exploration and application of the concept and current development of translational medicine.With the aid of concept and mode of translational medicine,TCM techniques,therapies and approaches in clinic will be reserved,explained,inherited and developed.
关键词:translational medicine;two-way channel;Chinese medicine
摘要:Translational medicine is a systematic medical system combining closely basic research and clinical application.The core ideology is to guide the whole research process with the thought of patient-centered,push forward the transformation of medical research idea,and shorten rapidly the distance between fundamental and clinic.Translational medicine,a research mode integrated multiple disciplines,accords with the inner objective law of medical science development and will be a new power promoting medicine development in 21st century.The substance of translational medicine has been investigated through a big sample screening of brain health in Beijing communities and enlightenment from the intervention of cognitive impairment with Chinese medicinal.
关键词:translational medicine;community screening;intervention with Chinese medicinal;biomarker;mild cognitive impairment
摘要:Translational medicine has emerged because serous disconnection between basic medicine and clinical medicine,which gets general concerning and its development is rapid.As translation medicine and TCM have a higher uniformity in operational mode,ideas and therapeutic approaches,the relative ways were discussed in the paper for TCM modernization from the angle of translational medicine.
摘要:Senile cognitive dysfunction is a severe disease endangering the health of older people as aging of population.Smoking,as a modifiable factor,has received more and more attentions because its influence on senile cognition.Through the discussion on the relationship between smoking and senile cognitive dysfunction,smoking is thought as a risk factor influencing senile cognition.The development of community health education is improved based on the concept of translational medicine and promoting the use of basic research to clinical practice,and the purpose is to increase the awareness rate of senile cognitive dysfunction,prolong and stop its occurrence and improve life quality of older people.
关键词:smoking;senile cognitive dysfunction;translational medicine;community health education
摘要:Standard is a sign of discipline mature degree and inevitable demand of TCM discipline development.During the period of Eleventh Five-Year Plan,the national and international standardization of Chinese medicine have made great development,but there are still protruding problems in cognition,research and overall coordination.The authors proposed some suggestions from five aspects including time-to-space conversion,scientism,cultural conflict,domestic situation and conformity resources.
摘要:Objective To screen the patients with vascular risk factors from clinic by applying self-identification and screening stools,discuss the incidence and risk factors of cognitive impairment,and provide evidence for early identification of vascular cognitive impairment(VCI).Methods Taking Mini-Mental State Examination(MMSE) and Montreal Cognitive Assessment(MoCA) as diagnosis basis,601 patients with vascular risk factors were divided into normal group,mild cognitive impairment group(mVCI group) and vascular dementia group(VD group).The incidence and risk factors of cognitive impairment were analyzed.Results Among 601 patients,230 in normal group,215 in mVCI group and 165 in VD group.There were 380 patients with cognitive impairment in 610 patients(62.3%).The sexual distribution was treated with chi-square test in three groups and results showed no significant difference in ratio of male and female(P>0.05).The age distribution was treated with variance analysis and the result showed a statistical significance(P<0.01).Conclusion The screening has found that most of patients have cognitive impairment in varying degrees,which indicates it is very important that early identification and screening for cognitive function in the patients with vascular risk factors.The sex was not risk factor but age is one of risk factors in the patients with vascular risk factors.
LANG Hai-yan1,SU Wei2,CHEN Xin-yi1,DING Xiao-qing2,GUO Ming2,LIU Jun-xia2
Vol. 19, Issue 1, Pages: 28-30(2012)
摘要:Objective To observe the influence of Yiqi Yangxue Huoxue Fang on platelet parameters in the patients with refractory idiopathic thrombocytopenic purpura(RITP).Methods The patients with RITP(n=40) were included into the treatment group treated Yiqi Yangxue Huoxue Fang,and other health people(n=36),into the control group.The platelet count(PLT),palteletcrit(PCT),mean platelet vojume(MVP) and platelet distribution width(PDW) in treatment group were compared with those in control group before the treatment,and were compared and observed in treatment group before and after the treatment.Results Before the treatment,PLT(P<0.01) and PCT(P<0.05) were lower and MPV and PDW were higher(P<0.05) in treatment group than those in control group.PLT and PCT increased significantly(P<0.01,P<0.05),and MPV and PDW decreased significantly(P<0.05) in treatment group after the treatment compared with those before the treatment.Conclusion Yiqi Yangxue Huoxue Fang can influence the platelet parameters like PCT,MPV and PDW besides increasing PLT in RITP patients
REN Ke,MA Ling-ling,LIU Mei-qi,ZHANG Jing-feng,BAI Yu,QIN Jian-guo,ZHANG Fan
Vol. 19, Issue 1, Pages: 31-32(2012)
摘要:Objective To observe the changes of oxyhemoglobin saturation before and after hemodialysis.Methods The patients(n=102) with maintained hemodialysis were divided into the group of spleen-kidney qi deficiency(n=16),group of spleen-kidney yang deficiency(n=12),group of liver-kidney yin deficiency(n=25),group of dual deficiency of qi and yin(n=13),group of dual deficiency of yin and yang(n=21) and group of dampness turbidity accumulating in interior(n=15).The oxyhemoglobin saturation was detected and compared in the patients respectively before and after hemodialysis.Results The oxyhemoglobin saturation was lower in all groups after hemodialysis than before and the difference was statistically significant(P<0.05).In the group of spleen-kidney yang deficiency,the oxyhemoglobin saturation was significantly lower than that in the other groups(P<0.05) after hemodialysis.Conclusion The oxyhemoglobin saturation was significantly lower in the patients of spleen-kidney yang deficiency after hemodialysis than that in the patients of other syndrome types.
关键词:hemodialysis;oxyhemoglobin saturation;TCM syndrome differentiation;spleen-kidney yang deficiency
摘要:The paper summarized the editorial work in 8 years since last meeting of editorial board at the occasion of the forth meeting of editorial board of Journal of Beijing University of Traditional Chinese Medicine(Clinical Medicine).①The journal has been run relying on university advantages,and contributions were solicited actively and columns were set up.The measures we have taken included establishing special columns for key departments,professional works in university and affiliated hospitals,and hot spots of society.②The tasks of edition and publication were fulfilled and published papers covered all clinical specialties and played a role in activating academic atmosphere.③The researches were conducted for improving journal quality and the achievements were practiced in the edition work.④The compilation norms were implemented from beginning to end.For 8 years the impact factor and total cited frequency of the journal increased year by year,and the journal has been compiled by Chinese Journal Fulltext Database(CJFD),China Academic Journal Comprehensive Evaluation Database(CAJCED),China Core Periodicals(Selection) Database,Chinese Medical Current Contents(CMCC) and China Biological Medical Journal Citations Database(CMCI).Aiming at the goal and task set by new editorial board,we will persist on our publishing purpose and operating policy,control the direction,play a guiding role,boost new medical ideas,and highlight practicality of our journal.The journal will depend on advantages of our university,especially the affiliated hospitals,put preferential policy given by the university into practice,gather more manuscripts in different ways,and promote constantly its academic level.
摘要:Objective To observe the distribution rules of TCM syndromes of diabetic nephropathy(DN),and offer the basis for further study on causes,pathogenesis and syndrome characteristics of DN.Methods All 180 patients were divided into stage-Ⅲ,stage-Ⅳ and stage-Ⅴ.A questionnaire of TCM syndromes of DN was made according to scale making methods,and a layered and cross-sectional survey was carried out in the patients.The obtained data were analyzed with frequency statistics.Results In stage-Ⅲ,qi deficiency syndrome and yin deficiency syndrome were common and the manifestations of internal heat syndrome,blood stasis syndrome and phlegm-damp syndrome were also observed.In stage-Ⅳ,there were blood deficiency syndrome and yang deficiency syndrome besides syndromes in stage-Ⅲ and the manifestations of water-damp syndrome,phlegm-damp syndrome,internal heat syndrome,heat accumulation syndrome and blood stasis syndrome were also observed.In stage-Ⅴ,the syndromes of deficiency of the root were more severe and the manifestations of qi stagnation syndrome,depression heat syndrome,damp-turbidity syndrome,blood stasis syndrome and heat accumulation syndrome were also observed.Conclusion The TCM syndromes of DN have the characteristics of deficiency of the root and excess of the tip.Along with disease progress,the syndromes of deficiency of the root trend to multiple,but blood stasis and dampness go throughout the whole course of disease.
关键词:diabetic nephropathy;staged syndrome differentiation;information of TCM four examinations;TCM syndromes;symptoms
摘要:Diabetic nephropathy is one of serious complications of diabetes.The author discussed the therapy of dispersing wind and freeing the collateral vessels,based on the mechanism of inflammation and immune injury of diabetic nephropathy and relevant TCM theory,from the aspects of diabetic cause and pathogenesis,effects of anti-inflammation and anti-immune injury of medications in the therapy of dispersing wind and freeing the collateral vessels.A new therapeutic thinking has been proposed form the treatment diabetic nephropathy with Chinese medicine.
关键词:diabetic nephropathy;inflammation;immunity;dispersing wind and freeing the collateral vessels;therapies of Chinese medicine
摘要:It is a new teaching mode to use courseware of TCM clinical teaching.The authors discussed the connotation of excellent courseware of TCM clinical teaching,combining with the experiences on courseware preparation and clinical teaching practice,from the aspects of total design,key points,structure and arrangement,gradations,content,writing,pictures,types,medical records and experiences of famous and senior TCM doctors,ancient medical records,video materials and clinical cases.