摘要:Objective To analyze initially the characteristics of leukoaraiosis mild cognitive impairment(LACI) by using the Montreal Cognitive Assessment(MoCA).Methods The patients with LACI(n=78) were selected and detected by using MoCA.The characteristics of LACI were analyzed initially and the degrees of cognitive impairment were compared in patients with different grades LA.Results The average total score of MoCA was(21.8±2.9) in 78 patients.The average score of visuospatial and executive function was(3.4±1.1) and 83.3% patients had visuospatial agnosia and executive function loss,that of denomination,(2.8±0.6) and 17.9% had anomia,that of attention and calculation,(5.3±1.0) and 46.2% had attention deficit and dyscalculia,that of linguistic competence,(1.6±0.8) and 88.5% had aphasia,that of abstract thinking,(0.9±0.7) and 76.9% had impaired abstract thinking,that of delayed memory,(1.8±1.3) and 98.7% patients had impairment of delayed memory,and that of orientation,(5.9±0.4) and 9.0% had unorientation.The total score of MoCA and scores of denomination,attention and calculation were lower in patients with grade 3 LA than those in patients with grade 1 LA(P<0.05),and the score of linguistic competence was lower in patients with grade 3 LA than that in patients with grade 1 LA and grade 2 LA(P<0.05).The scores of other indexes had no statistical differences compared among all groups.Conclusion The patients with LACI have the manifestations of impairment in multiple cognitive fields,among which the most common one is impairment of delayed memory,and others include aphasia,visuospatial agnosia,executive function loss,impaired abstract thinking,attention deficit and dyscalculia.There is a correlation between grades of LA and degree of cognitive impairment.
摘要:The occurrence rate of vascular dementia is increasing year by year,and it has a long and ingravescence course.At present the awareness rate,rate of visiting doctor and treatment rate are lower,and there are not satisfactory therapeutic plans.Some measures should be taken including ancient literature database,personalized prevention and treatment,animal research model,biomarker database,community health improvement and new ideas and methods for preventing and curing vascular dementia.The key in construction of translational medicine system of preventing and treating vascular dementia with Chinese medicine is to build talent group and governmental support.
关键词:vascular dementia;translational medicine;Chinese medicine;prevention and treatment
摘要:Vascular dementia(VD) is a common and frequently-occurring disease,which is influencing seriously the life quality of aged people.The authors analyzed and summarized the etiology and pathogenesis of VD and therapeutic progress in clinic based on scientific research achievements and literature about treatment of VD with Chinese medicine.They thought that the important factors in the development of VD included deficiency of zang-fu organs,disorder of qi and blood and phlegm-stasis obstructing orifices,and the key points included accumulation of phlegm-stasis,production of turbid-toxin and injury of collaterals and marrow,the therapeutic period was divided into early,middle and late stages or platform,wave and glide stages,TCM therapies for VD included tonifying kidney,activating blood circulation and resolving phlegm,tonifying kidney,tonifying qi and activating blood circulation,activating blood circulation and freeing calleterals,and activating blood circulation and resolving phlegm,and acupuncture therapies for VD included body acupuncture,integration of acupuncture and medicinal,eye acupuncture,ear acupoint pressing combining with moxibustion,and acupoint application with Chinese medicinal.In the future,the pathogenesis and effective therapies for vascular cognitive impairment no dementia(V-CIND) should be explored for preventing,diagnosing and intervening VD early besides improving the study on the diagnosis and treatment of VD.
关键词:vascular dementia;treatment with Chinese medicine;current situation
摘要:Objective To observe the curative effect of Fufang Ejiao Jiang on chemotherapy-induced anaemia.Methods The patients(n=92) with anaemia after treating tumors with chemotherapy were randomly divided into treatment group(n=45) and control group(n=47).Two groups were given routine chemotherapy and supporting therapy,and treatment group was additionally given oral Fufang Ejiao Jiang.The changes of hemoglobin(Hgb),TCM symptom scoring and scores of Karnofsky performance scale(KPS) were observed in two groups.Results The difference in Hgb before and after the treatment was better in treatment group compared with control group(P<0.05),TCM symptoms were relieved more in treatment group than those in control group(P<0.05),and improvement of KPS scores was better in treatment group than that in control group(P<0.05).Conclusion Fufang Ejiao Jiang can delay the occurrence of chemotherapy-induced anaemia,ameliorate clinical symptoms of anaemia and raise patients’ life quality.
关键词:chemotherapy-induced anaemia;Chinese medicine;therapy of fortifying spleen and tonifying kidney;Fufang Ejiao Jiang
摘要:Objective To observe the curative effect of Professor GUO Zhi-qiang’s empirical formulas on cervicitis.Methods The patients with cervicitis(n=115) treated by Professor GUO Zhi-qiang were analyzed retrospectively,and the distribution of syndrome types of vaginal discharge was observed.The curative effect of Chinese medicinal for treating different types of vaginal discharge was compared,and the curative effects of Chinese medicinal for treating cervicitis and sexual bleeding were observed.Results Among 115 patients,there were 57 with syndrome of damp-heat pouring down into lower energizer(49.57%),29 with syndrome of kidney yang deficiency(25.22%),13 with syndrome of kidney yin deficiency(11.30%),and 16 with syndrome of spleen deficiency with dampness encumbrance(13.91%).After treatment with Chinese medicinal,there were 20 cases cured,16 with obvious effects,14 with effects and 7 without effects in patients with syndrome of damp-heat pouring down into lower energizer.There were 3 cases cured,3 with obvious effects,9 with effects and 14 without effects in patients with syndrome of kidney yang deficiency.There were 1 case cured,2 with obvious effects,4 with effects and 6 without effects in patients with syndrome of kidney yin deficiency.There were 2 cases cured,2 with obvious effects,6 with effects and 6 without effects in patients with syndrome of spleen deficiency with dampness encumbrance.The empirical formulas had different curative effects for different types of vaginal discharge(P<0.05),and the total effective rate was highest in patients with syndrome of damp-heat pouring down into lower energizer.There were 36 cases with obvious effects and 59 with effects in patients with cervical erosion,and the total effective rate was 82.61%.There was only one case with sexual bleeding and other 9 without once more.Conclusion The syndrome of damp-heat pouring down into lower energizer is common in the patients with vaginal discharge,and on which the empirical formulas have the best curative effect.GUO Zhi-qiang’s empirical formulas also have some curative effect on cervical erosion and sexual bleeding.
摘要:Objective To observe the curative effect of Kuiyang You on diabetic foot ulcer.Methods All 50 patients with diabetic foot ulcer(type of damp-heat accumulation) were randomly divided into treatment group(n=28) and control group(n=22).Besides of basic treatment,treatment group was treated with Kuiyang You externally and control group,with Qufu Shengji Gao externally.A therapeutic course was 28 days.The status of ulcer healing and integrals of ulcer area after treatment were compared between two groups.Results The results of ulcer healing showed that in treatment group,there were 12 cases cured(42.86%),10 with obvious effects(35.71%),4 with effects(14.29%) and 2 without effects(7.14%),and the total effective rate was 92.86%.In control group,there were 5 cured(22.73%),5 with obvious effects(22.73%),4 with effects(18.18%) and 8 without effects(36.36%),and the total effective rate was 63.64%.The curative effect was better in treatment group than that in control group(P<0.05).The integrals of ulcer area showed that the difference in integrals of infiltrative zone around ulcer had no statistical significance(P>0.05) between two groups after treatment.In treatment group,the integrals of granulation time,swelling around ulcer,fester exudation,reduced rate of ulcer area and pain all decreased significantly compared with control group(P<0.05).Conclusion Kuiyang You used externally has a good curative effect on diabetic foot ulcer.
摘要:Objective To observe the curative effect of movable cupping therapy combing Chinese medicinal on common plaque psoriasis.Methods The patients(n=32) were given movable cupping therapy on the base of syndrome differentiation and oral Chinese medicinal.The area of plaque psoriasis,severe degree index(PASI score) and curative effect were observed 2 weeks and 4 weeks after the treatment.Results In 32 patients,PASI score was(17.97±6.24) before treatment,(7.61±2.53) two weeks after treatment and(2.48±1.18) four weeks after treatment.The difference in PASI score before treatment compared with that 2 weeks after treatment showed a statistical significant(P<0.01),and that before treatment compared with that 4 weeks after treatment showed a statistical significant(P<0.01).The difference in PASI score 2 weeks after treatment compared with that 4 weeks after treatment showed a statistical significant(P<0.01).The total effective rate was 75.00% after two weeks and 87.50% after four weeks.Conclusion The movable cupping therapy combing Chinese medicinal has a good curative effect on common plaque psoriasis.
关键词:plaque psoriasis;movable cupping therapy;treatment with Chinese medicine;external treatment with Chinese medicine
LI Qing1,XIA Yun2,MU Yu-jie1,WANG Yu-yi1,LIU Jian-ping1#
Vol. 19, Issue 3, Pages: 28-33(2012)
摘要:Objective To evaluate methodology quality and reporting quality of TCM systematic reviews and Meta-analyses documents published in domestic Chinese journals,and compare them with quality evaluation results of systematic reviews published before.Methods The documents were retrieved from China National Network Knowledge Infrastructure(CNKI),Chinese Scientific Journal Database(VIP),Chinese BioMedical Literature Database(CBM) and Wanfang Database,and the retrieving duration was from the building time of these databases to Dec.2011.All therapeutic systematic reviews and Meta-analysis documents taking TCM therapies as interventional measures were identified.According to 11 items in AMSTAR scale and 27 items in PRISMA,the relative information was extracted and the methodology quality and reporting quality were evaluated.Results There were totally 666 documents of TCM systematic reviews and Meta-analysis extracted,and the number of documents showed a increasing trend year by year.The results of methodology quality evaluation showed that the majority of documents was lower in methodology quality and there was no relation between methodology quality and publishing years(P=0.121).The comparison between the documents published after 2007 and those published before showed that the report titles,document quality evaluation,course of study and selection and retrieval had been improved,but there were still some problems,i.e.lack of previous research plan,explanation of relative conflict of interest and excluded literature list,and application of composite ending index.Conclusion The quality of TCM systematic reviews and Meta-analyses documents published in domestic Chinese journals needs to be improved,and the training of methodology should be strengthened for research personnel working in TCM systematic reviews.
关键词:traditional Chinese medicine;systematic reviews;Meta-analyses;methodology;quality evaluation
摘要:Acupuncture Clinical Practice Guideline of Stroke Supranuclear Paralysis is the research result of a subproject of West Pacific Region program supported by WHO,Clinical Practice Guideline of Chinese Evidence-Based Medicine.Acupuncture has a good curative effect on stroke supranuclear paralysis and there is a lot of literature at ancient and modern time about acupoint selection and operation for treating this disease.It is a pioneering work to edit and write clinical practice guideline.The research group finally finished the guideline through questionnaire,group discussion,expert consultation,expert demonstration,and determination of some questions including disease choice,clinical problems,search and evaluation of literature and formation of recommendation proposal.The paper read and explained Acupuncture Clinical Practice Guideline of Stroke Supranuclear Paralysis from 4 aspects including background,difficult points and countermeasures,main content and characteristics.
关键词:clinical practice guideline;acupuncture;stroke supranuclear paralysis;reading
摘要:In Chinese medicine,the occurrence of phlegm-fluid retention is mainly induced by the dysfunction of lung,spleen and kidney.Hypersecretion of airway mucous is the pathological feature of chronic obstructive pulmonary diseases(COPD) as well as important factor influencing its condition and prognosis,and its clinical characteristics are accorded with the features of syndrome of phlegm-fluid retention.The authors presented that the therapy for hypersecretion of airway mucous of COPD stable stage is supplementing qi and fortify spleen,and diffuse lung to resolve phlegm based on the pathogenesis of syndrome of phlegm-fluid retention and theory of spleen being source of phlegm and lung being storage of phlegm in Chinese medicine.
关键词:chronic obstructive pulmonary disease;stable stage;hypersecretion of airway mucous;syndrome of phlegm-fluid retention;supplementing qi and fortify spleen;diffuse lung to resolve phlegm
摘要:The postgraduate education is in an important period from training academic talents transiting to training applicative ones(postgraduates of professional degree).The construction of innovation base has resolved the biggest problem in the transiting process:practice base of postgraduate education.Aiming at the problems in the innovation base of postgraduate education,the paper suggested some relative measures,including setting up leading group,improving substantial cooperation,reforming training mode,promoting production-learning-research combination,playing fully diffusive role of innovation base,enlarging base range,doing well in mid-term evaluation and propelling the development of professional postgraduate education.
摘要:Otorhinolaryngology is one of characteristic disciplines in clinical medicine with highly speciality.The clinical skills are not easy to master so clinical prabatoinary is very important for students.The enthusiasm and initiative of students’ can be mobilized through arousing their learning interest.With the examinations of ear,nose and throat and case report writing,the clinical skills of students’ have been trained.The quality of clinical prabatoinary will be improved through refining and standardizing the criterion of quantitative assessment of prabatoinary in department of otorhinolaryngology.
关键词:department of otorhinolaryngology;clinical skill training;quantitative assessment