摘要:The evolution, prognosis and treatment of syndrome of phlegm heat and bowel excess of stroke after applying therapy of resolving phlegm and relaxing bowels were summed up. The patients with different physiques, causes and pathogeneses will have different syndrome evolution and prognosis including freeing of bowels qi, reducing of phlegm heat, temporary resolving of bowel excess without freeing of bowels qi or without reducing of phlegm heat, and bowel qi obstruction with intense phlegm-heat and wind-fire. The authors indicate that syndrome of phlegm heat and bowel excess derives from the same pathogeneses of stroke including qi movement disorder, phlegm-heat retained in middle energizer and disorder of upbearing and downbearing. So freeing of bowels qi and reducing of phlegm heat are closely related to disease tendency and outcome.
关键词:therapy of resolving phlegm and relaxing bowels;stroke;syndrome of phlegm heat and bowel excess
摘要:Objective To study the curative effect and safety of TCM external treatment on breast hyperplasia. Methods By applying randomized double-blinded placebo-parallel-controlled method, 260 patients with breast hyperplasia were selected from 5 research centers, and then divided into treatment group and control group according to a proportion of 1 : 1. The treatment group was treated with Sanjie Rupi Gao applied on the best pain points of bilateral breasts one piece each side for 7 hours a day, and control group was treated with simulation agent. Every group was treated for 2 menstrual cycles but not treated during menstrual period. The indexes of breast painand lump were observed in two groups. Results The total effective rate was 73.2% in treatment group and 31.8% in control group after treatment. The comparison had statistical significance between two groups. Conclusion Sanjie Rupi Gao has a reliable curative effect without adverse reactions in the treatment of breast hyperplasia.
关键词:breast hyperplasia;external treatment with Chinese medicinal;Sanjie Rupi Gao
HE Xiao-jin,PAN Li-qun,JIANG Wei-hua,XU Feng,JIANG Hong-Jie,JING Hai-bo
Vol. 20, Issue 2, Pages: 9-14(2013)
摘要:Objective To observe the curative effect and safety of Sanhan Zhitong Plaster in the treatment of cold-dampness obstruction syndrome of knee osteoarthritis (KOA). Methods KOA patients (n=578) from 4 research centers were divided, accordind to a proportion of 2:2:1, into group A (n=233, treated with Fufang Nanxing Zhitong Plaster), group B (n=230, treated with Shangshi Jietong Plaster) and group C (n=115, treated with acrylics pressure-sensitive adhesive plaster), once a day for 6 days. The cure rate, effective rate, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), integrals of TCM syndromes and adverse effects after medication were compared among three groups before and after treatment. Results All data were analyzed by using Full Analysis Set (FAS) and Per-Protocol population (PP). The curative effect was the best in group A after knee pain scoring with Visual Analogue Scale (VAS). The change tendency of WOMAC had statistical significance in three groups before and after treatment. The curative effect on TCM syndromes was the best in group A after data analysis with FAS. There were no serious adverse reactions observed related to experimental medicinal. Conclusion Sanhan Zhitong Plaster is safe and effective in the treatment of cold-dampness obstruction syndrome of KOA
关键词:external plaster;knee osteoarthritis;dispelling cold and relieving pain;randomized double-blinded controlled trials;multi-center study
摘要:Objective To establish TCM comprehensive external treatment plans, manipulation specification and curative effect evaluation standard of ulcer period of diabetic foot for providing the therapeutic guide through standardized clinical study. Methods The plan of central randomized, positive controlled and multi-center clinical trials were managed by applying the third-party data, and TCM comprehensive external treatment plans for ulcer period of diabetic foot from grade Ⅱ to grade Ⅳ were summed up in 190 cases studied by national 5 branch-centers. Results The differences in wound healing rate, wound closure index, curative effect of disease and curative effect of syndromes had statistical significance respectively compared between treatment group 1 or treatment group 2 and control group (P<0.05). There was no difference between treatment group 1 and treatment group 2(P>0.05) Conclusion The therapeutic principles for ulcer period of diabetic foot is supporting the root and binding toxin, and dispelling putridity and promoting regeneration. TCM comprehensive external treatment plans are effective therapies for reducing and controlling toxin, and keeping the maximum of functional tissues. The plans, with scientific measures and tests of TCM syndrome quantification evaluation and reliable curative effect, canbe used in the treatment of ulcer period of diabetic foot.
关键词:ulcer period of diabetic foot;TCM external treatment;multi-center clinical study
摘要:Objective To review the curative effect and safety of Dinggui San applied on umbilicus combining Qianlie ’ an Shuan on type Ⅲ prostatitis (type of qi stagnation and blood stasis). Methods The patients (n=160) were,accordingtomulti-centeredandstandardizedcontrolledmethod,dividedintoDingguiSancombiningQianlie ’ an Shuan group (group A) and Qianlie ’an Shuan group (group B). One particle of Qianlie ’ an Shuan was intruded into anus before sleeping, and Dinggui San [Dingxiang (Flos Caryophylli, 0.3 g) and Rougui (Cortex Cinnamomi,1g)] mixed well with rice vinegar and applied on umbilicus once a day for 4 weeks. The curative effect was reviewed by using NIH-CPSI and TCM syndrome scoring, and adverse reactions were recorded at the same time. Results The results of NIH-CPSI showed that the total effective rate was 83.8% in group A and 68.4% in group B (P<0.05). The results of TCM syndrome scoring showed that the total effective rate was 78.4% in group A and 64.5% in group B (P<0.05). There were no adverse reactions observed. Conclusion Dinggui San applied on umbilicus combining Qianlie ’an Shuan is safe and effective to type Ⅲ prostatitis (type of qi stagnation and blood stasis).
摘要:Objective To establish a method for standardized evaluation on curative effect of external Chinese medicinal for treating psoriasis of blood-heat type. Methods Through retrospective study, literature arrangement, expert questionnaire and Optimization argument, an evaluation method was formed initially. The multi-centered, big sampled and randomized double-blinded placebo-controlled clinical trials were designed according to demand of evidence-based medicine, taken Pulian Gao treating psoriasis of blood-heat type as an example, for verifying and summing up the evaluation method. The scores of psoriasis area and severity index (PASI) and TCM syndromes were regulated and improved. Results An evaluation system of curative effect was initially established including evaluation of curative effect on disease, evaluation of curative effect on TCM syndromes and evaluation on safety. Conclusion The evaluation method established in this study is comprehensive, accurate and objective in the evaluation on the curative effect of external Chinese medicinal for treating psoriasis of blood-heat type.
关键词:psoriasis;TCM external treatment;evaluation methods of curative effect
摘要:According to the experience on conducting randomized controlled trials (RCT) of needling, the authors summed up some key points and notes of methodologic issues in implementation of acupuncture RCT. There were 6 aspects that were should be paid special attention to, including ①influence factors and control of variability in acupuncturists ’ manipulation process, ②selection and implementation of placebo-acupuncture control, ③patient compliance, ④evaluation on safety of needling, ⑤personal arrangement, and ⑥clinical monitoring. The quality of the implementation of acupuncture RCT is one of the decisive factors in the whole study, which should be concidered cautiously.
关键词:acupuncture;needling;randomized controlled trial;clinical trial;standard operating procedure;compliance;quality control
摘要:Objective To review the curative effect and influence of Chuangxion Dingtong Yin in the prophylactic treatment of syndrome of liver wind complicated by stasis of migraine. Methods By applying multi-centered, perspective, randomized and double-blinded placebo-controlled method, treatment group (n=86) was orally given granules of Chuangxion Dingtong Yin and necessary analgesics for 12 weeks and control group (n=42) was orally given placebo and necessary analgesics for 12 weeks. The indexes of quality of life and times of headache attack were reviewed respectively before and after treatment. Results The difference in total index score of quality of life and average of prospective items had statistical significance between two groups (P<0.05). The different values in times of headache attack before and after treatment had significance between two groups ( P <0.05). Conclusion The prophylactic treatment of migraine with Chuangxion Dingtong Yin can effectively improve quality of life and reduce times of headache attack in the patients.
关键词:Chuangxion Dingtong Yin;migraine;syndrome of liver wind complicated by stasis;quality of life
SHI Zhi-hong,WANG Peng,CHEN Sheng,FU Yu,WANG Peng,WANG Yu-ming,ZHAO Ji-ping
Vol. 20, Issue 2, Pages: 47-49(2013)
摘要:Objective To review the curative effect of needling therapy of regulating mind on persistent allergic rhinitis (AR). Methods The eligible subjects were randomly divided into treatment group and control group. The treatment group (n=20) was treated according to set acupoints and needling methods in established plan three times a week for 4 weeks, and control group (n=16) was treated with oral cetirizine once a day for 4 weeks. The total nasal symptom score (TNSS) was observed. Results The comparison within the same group showed the difference had statistical significance (P<0.05) from the 3 rd week in treatment group and the 1 st in control group. The average baseline of TNSS decreased in two groups after treatment (P<0.05). The total effect of relieving nasal main symptoms in treatment group was similar to that in control group (P>0.05). Conclusion The needling therapy of regulating mind is an effective therapy for treating AR.