摘要:The authors summed up the onset and damage of the disorder of intestinal function after stroke, and discussed the mechanism from the changes of brain-gut axis. The study results showed that after stroke the stress of brain-gut peptide increased and correlated to stroke degree. The level of motilin was significantly higher in the patients with syndrome of phlegm heat and bowel excess than in those with other syndromes. The effective mechanism of therapy of resolving phlegm and relaxing bowels was summarized from regulating brain-gut axis, inhibiting inflammatory reaction and improving hemorrheology.
关键词:stroke;phlegm heat and bowel excess;brain-gut axis
摘要:Green treatment of tumor, being different from traditional treatment mode, aims at keeping patients’ living quality, which demands that guarantee of basic living quality is the precondition for prolonging life. The major treatment means include minimally invasive surgery, Chinese medicinal and biological therapies. Under the guidance of TCM, modern minimally invasive technology is introduced into TCM surgery system for modernizing TCM surgery. The purpose is to combine internal and external treatment, achieve curative effect in the context of protecting healthy qi (normal structure and function), and realize sustainable and repeatable treatment of tumor. The green treatment of tumor provides a new therapeutic strategy for the patients being older or weak or those with failing routine treatment, and it is a helpful trial in the modernization of TCM therapeutic technology.
关键词:malignant tumor;green treatment;modern TCM surgery
摘要:Objective To observe the curative effect of Chinese medicinal combining argonhelium knife cryosurgery on advanced lung cancer. Methods The patients (n=68) were treated with Chinese medicinal (oral decoction according to syndrome differentiation) and argon- helium knife cryosurgery (after failing chemoradiotherapy and targeted drug treatment). Results According to effect evaluation criterion, the total effective rate was, respectively, 88.2%, 81.3% and 61.5% after the surgery for 3 months, 6 months and 12 months. The adverse reactions were mild. Conclusion Chinese medicinal combining argonhelium knife cryosurgery is an effective therapy for advanced lung cancer.
关键词:argon-helium knife;cryosurgery;Chinese medicinal;advanced lung cancer
摘要:Objective To observe the curative effect and safety of Huachansu Injection poured into thorax and abdomen in the treatment of malignant hydrothorax and ascite, and discuss the mechanism initially. Methods The patients with malignant hydrothorax and ascite (n=30) were chosen and given the perfusion treatment in thorax and abdomen three times a week (250 mL normal saline and 40 mL Huachansu Injection) after draining pleuroperitoneal fluid. One therapeutic course was two weeks. After one therapeutic course, the review on curative effect was conducted according to quantity of pleuroperitoneal fluid, tumor marker (TM), RBC count and symptoms. Results The total effective rate was 46.67% . The red color became lighter in 75.00% (12/16) patients with bloody hydrothorax and ascite by naked eye. The levels of TM and RBC count decreased significantly in the most of patients. Conclusion The perfusion treatment of Huachansu Injection has certain curative effect on malignant hydrothorax and ascite diagnosed as syndrome of dampness heat toxin.
关键词:malignant hydrothorax and ascite;Huachansu Injection;perfusion treatment in thorax and abdomen;bloody hydrothorax and ascite;local syndrome differentiation of TCM
摘要:Objective To observe the curative effect of external Chinese medicinal with actions of clearing heat and draining dampness (self-made Zhiyang Pingfu Ye) on epidermal growth factor receptor inhibitors (EGFRIs)-related acne rash, and review the safety. Methods The patients (n=120) with malignant cancer suffering from acne rash after using EGFRIs diagnosed pathologically (syndrome types of wind heat or dampness heat) were chosen and then randomly divided into treatment group (n=80) and control group (n=40). The treatment group was treated externally with self-made Zhiyang Pingfu Ye, and control group, with erythromycin ointment all for 14 days. The changes of acne rash and safety indexes of routine blood test and liver and kidney functions were observed in two groups before and after treatment. Results In the aspect of abating acne rash, there were 57 cases with curative effect and 23 being stable in treatment group, and 7 with curative effect and 33 being stable in control group. In the aspect of relieving pruritus, there were 45 cases with curative effect and 35 being stable in treatment group, and 3 with curative effect and 37 being stable in control group. The analysis of SPSS 7.0 software showed that all P<0.05 with statistical significance. The curative effect of Chinese medicinal was better than that of erythromycin ointment. There were no significant hematological toxicity and adverse reactions observed in the tests of routine blood test and liver and kidney functions. Conclusion Self-made Zhiyang Pingfu Ye has significant curative effect on EGFRIs-related acne rash in abating acne rash and relieving pruritus and has no adverse reactions.
关键词:epidermal growth factor receptor inhibitors;acne rash;malignant cancer;pruritus;self-made Zhiyang Pingfu Ye;clearing heat and draining dampness;Chinese medicinal used externally
摘要:Objective To observe the effects of Yangyin Qingfei Fang in relieving clinical symptoms and improving quality of life in the patients with radiation pneumonitis. Methods The patients (n=60) were randomly divided into treatment group and control group (each n=30). The treatment group was treated with Yangyin Qingfei Fang combining prednisone, and control group with only prednisone. The Karnofsky scoring, grading of radiation therapy oncology group (RTOG) standard, Watters scoring and TCM symptom scoring were observed in two groups before and one month after treatment. Results Compared with control group, Watters scoring, Karnofsky scoring, short breath and lack of strength were significantly improved or relieved in treatment group (P<0.05, P<0.01). RTOG grading and cough had no statistical difference between two group (P>0.05), but treatment group had relieving trend. Conclusion Yangyin Qingfei Fang combining prednisone can effectively relieve symptoms and improve quality of life in patients with radiation pneumonitis, and the curative effect is better than simply use of hormone.
LU Yao,WANG Jia-xi,PEI Gui-fang,DING Lei,LIU Wen-na #
Vol. 20, Issue 4, Pages: 26-29(2013)
摘要:Objective To investigate the examination of laryngoscope as the supplement of TCM inspection and its scientificity based on chronic laryngitis (syndrome of blood stasis and phlegm coagulation). Methods A epidemiological survey was carried out on the diagnostic indexes in 694 patients with chronic laryngitis (syndrome of blood stasis and phlegm coagulation). And then the patients were divided into groups according to whether or not they had vocal nodules. The distribution of single symptom or sign was observed, and reasonability of designed diagnostic indexes was discussed through the correlation analysis on TCM syndromes, single symptom or sign and integrals of laryngoscope. Results Besides of vocal nodules, the occurrence rate of single symptom or sign was higher. Hoarseness was severer in the patients with vocal nodules than in those without. The integrals of TCM syndromes were correlated to laryngoscope integrals and single sign in the patients with or without vocal nodules. In the patients without vocal nodules, only hoarseness and dry throat were significantly correlated to the integrals of laryngoscope, and in those with vocal nodules, every single symptom was correlated to the integrals of laryngoscope. Conclusion The selection of diagnostic indexes are correct and the design of TCM symptoms scoring table are reasonable. The examination of laryngoscope can help to increase the accuracy of TCM syndrome diagnosis. Vocal nodules can be taken as a specific index for diagnosing chronic laryngitis (syndrome of blood stasis and phlegm coagulation), but when reviewing the curative effect stratified analysis should be conducted.
关键词:chronic laryngitis;syndrome of blood stasis and phlegm coagulation;syndrome indexes;epidemiological survey;correlation analysis
LI Zhi-hong 1,CHEN Jian-xin 2,GUO Zhi-ling 2,Guiding: TIAN De-lu 1
Vol. 20, Issue 4, Pages: 30-33(2013)
摘要:Objective To discuss Professor TIAN De-lu’s medication laws in treatment of functional dyspepsia through proper statistical methods. Methods On ACCESS platform, the structural medical record template was established for collecting Professor TIAN De-lu’s therapeutic information in clinic. The information of all patients (875 medical records) was input into database according to standard writing format of outpatient medical record. The data mining was conducted at three levels—single medicinal, coupled medicinal and core combinations of common medicinal. Results The single medicinal used commonly by Professor TIAN De-lu are Zisugeng (Caulis Perillae), Zisuzi (Fructus Perillae), Xiangfu (Rhizoma Cyperi), Chenpi (Pericarpium Citri Reticulatae) and so on. The common coupled medicinal are Zisugeng and Xiangfu, Banxia (Rhizoma Pinelliae) and Huangqin (Radix Scutellariae), Huanglian (Rhizoma Coptidis) and Wuzhuyu (Fructus Evodiae) and so on. The core medicinal combinations include Zisugeng, Zisuzi, Xiangfu, Chenpi, Pugongying (Herba Taraxaci), Weilingxian (Radix Clematidis), Yujin (Radix Curcumae) and so on. All above-mentioned single medicinal, coupled medicinal and core medicinal combinations are commonly used by Professor TIAN De-lu and reflected his therapeutic thought and clinical experience. Conclusion The results of this study reflect the major medication laws and characteristics in treatment of functional dyspepsia by Professor TIAN De-lu.
摘要:Objective To study the mechanism of limb function recovery through investigating the reactions of immediate cerebral functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) in the patients with hemiplegia after stroke and treated with scalp acupuncture. Methods The patients were treated with scalp acupuncture for clinical observation and finding out effective and ineffective phenomenons, and two patients (one had curative effect and one had not) were given scanning of fMRI and DTI on the passive movement of hemiplegia limb and scalp acupuncture actions. Results The cerebral activating areas of limb movement were similar in the two patients, while the cerebral activating effectiveness of scalp acupuncture had significant difference. The activating range was correlated to the effectiveness of scalp acupuncture. The results of DTI showed that there was difference in the injury degrees of pyramidal tract fibers. Conclusion The recovery of movement function is closely related to cerebellar function after stroke, and scalp acupuncture has some effects on movement regulation. The curative effect of scalp acupuncture is correlated to cerebral activating reaction. The position, size and symptoms of hemiplegia injury are closely related to the recovery degree and mechanism of neural function.
关键词:hemiplegia;scalp acupuncture;functional rehabilitation;cerebral functional magnetic resonance imaging;diffusion tensor imaging
摘要:Objective To observe the curative effect of the injection in Zusanli(ST36)with autologous venous blood on acne(syndrome of phlegm-damp and static blood obstruction). Methods The patients(n=150)were divided into two groups(each n=75)according to randomized and voluntary principle. The control group was given modified Erchen Tang combining Taohong Siwu Tang,and treatment group was given the injection in ST36 with autologous venous blood besides of the same treatment as control group once a week and four times as one therapeutic course. The curative effect was observed after treatment for two therapeutic courses. Results The total effective rate was 97.3% in treatment group and 86.7% in control group,and the difference was statistically significant between two groups(χ2 =4.78,P<0.05). Conclusion Chinese medicinal combining acupoint injection with autologous venous blood has better curative effect than simple Chinese medicinal on acne(syndrome of phlegm-damp and static blood obstruction).
关键词:autologous venous blood;acupoint injection;acne;phlegm-damp and static blood obstruction
摘要:Flow charts are used to record the process and results of retrieving and screening systematic review literature. The table of included-excluded trial characteristics and table of bias risk assessment can sum up the important information of items related to the features of interventions and methodological quality. The table of intervention effect assessment and table of main outcome summarization can sum up the size and direction of effective values of major outcome indexes in single or gathered trials. The table of Chinese medicinal component analysis can sum up the constituents and dosages in the studies taken Chinese medicinal as intervention. The table of acupoint selection analysis can sum up the selection of acupoints in the studies taken acupuncture as intervention. The report quality of randomized controlled trials for reviewing the curative effect of Chinese medicinal or acupuncture can be reviewed by using the checklist of the herbal CONSORT statement and STRICTA checklist. Furthermore, the table of adverse event summarization can be used for summing up the possible side effects of interventions and comparison results of occurrence rate of adverse events between intervention group and control group.
关键词:systematic review;meta-analysis;design of charts
摘要:<正>经国家新闻出版广电总局批准(批准文号:新出审字[2013]466号),《北京中医药大学学报(中医临床版)》正式更名为《现代中医临床》,英文名称Modern Chinese Clinical Medicine。原刊号CN11-4892/R作废,新编国内统一连续出版物号CN10-1157/R。自2014年始使用新刊名与新刊号。