摘要:As the complication of sub-health symptoms and lack of objective diagnosis and curative effect criterions,quality control is very important in the clinical intervention study of sub-health.Our research group has conducted a study on sub-health intervened with Chinese medicinal and non-medicinal intervention,and proposed several key points including determining study types,selective standard of subjects,target system of curative effect grading,measures for strengthening compliance,and importance and concrete content of quality control.
关键词:sub-health;clinical intervention with TCM;key points;quality control
摘要:Objective To observe the effect of exercise of baduanjin on TCM symptoms in people with fatiguepredominant sub-health.MethodsThe patients were divided into baduanjin cohort(n=62) and control cohort(n=67) by applying cohort study method.After observation for 6 weeks,all patients were required to fill a questionnaire of TCM symptoms respectively at beginning and the end of 6th week.The changes of TCM symptoms were observed in 2 cohorts.ResultsThe comparison in the scores of TCM symptoms between the end of 6th week and baseline showed that the scores of 19 symptoms(86.4%),including lassitude of spirit and forgetfulness,decreased significantly in baduanjin cohort(P<0.05),and the scores of only 4 symptoms,including shortness of breath and laziness to speak,and weakness of waist and knee,decreased significantly in control cohort(P<0.05).At the end of 6th week,there was significant difference in the scores of 14 symptoms(63.6%),including lassitude of spirit and vexation between two cohorts(P<0.05).ConclusionThe exercise of baduanjin has significant relieve effect on TCM symptoms in people with fatigue-predominant sub-health.
HE Li-juan,WANG Yu-lai,GUO Rong-juan,ZHAO Xiu-mei,LI Dan,MA Yu-feng,DU Ya-wei,YIN Ling
Vol. 20, Issue 6, Pages: 10-13(2013)
摘要:Objective To establish a rat model of liver qi depression syndrome by using methods of chronic restraint stress and isolation rearing,and to review the animal model through determination of ethology,macroscopic manifestations,laboratory indexes and counter evidence of medicines.MethodsAll of the rats(n=30) were randomly divided into control group,model group and Chaihu Shugan San group.In each group,the changes of macroscopic manifestations and body weigh were observed.The levels of plasma adrenocoticotropic hormone(ACTH) and corticosterone(CORT) were detected by using enzyme linked immunosorbent assay(ELISA) open-field test and sucrose water test.Chaihu Shugan San was used as counter evidence.ResultsThe rats in model group were listless with dry and disheveled hair,waded interests,watery stool and slowly weight gaining.In model group the scores of horizontal movement and vertical movement decreased significantly,dejection amounts increased,preference for sucrose decreased,and levels of plasma ACTH and CORT increased.Chaihu Shugan San had significant curative effects.ConclusionThe rat model of liver qi depression syndrome is successfully established by using methods of chronic restraint stress and isolation rearing.
关键词:liver qi depression syndrome;chronic restraint stress;rat model
摘要:Objective To observe the curative effect of Aidi Injection on tumor-associated depression.Methods By applying pragmatic randomized controlled methds,all patients were divided into treatment group(n=55) given intravenous drip of Aidi Injection and control group(n=52) given intravenous drip of Fufang Kushen Injection once a day for 14 days.The changes of HAMD-17 integrals were observed in patients before and after treatment.ResultsThe total effective rate was 28.8%(15/52) in control group and 40.0%(22/55) in treatment group(P<0.05).The effective rate on mild tumor-associated depression was 35.1%(13/37) in control group and 48.7%(19/39) in treatment group(P<0.05).ConclusionAidi Injection has a certain curative effect on tumor-associated depression.
摘要:Objective To observe the curative effect of Yangfei Xiaozhen Tang on EGFR-TKIs-related adverse skin reactions.MethodsThe patients(n=50) with non-small-cell lung cancer(NSCLC) and rash after taking EGFR-TKIs were randomly divided into two groups and respectively treated with Yangfei Xiaozhen Tang used orally combining washing(treatment group,n=25) and external pimecrolimus ointment(control group,n=25).The changes of rash grading,TCM syndromes and relief of quality of life(QOL) were observed in two groups.Results In treatment group,the rash grading was improved at all time points.After treatment for 30 days,the effective rate was 72% in treatment group and 44% in control group.The recovery rate of TCM syndromes was 92% in treatment group and 36% in control group after treatment.The scores of QOL were superior in treatment group after treatment for 14 days and 30 days.ConclusionYangfei Xiaozhen Tang used orally combining washing has good curative effect on EGFR-TKIs-related adverse skin reactions.
摘要:Objective To discuss distribution characteristics of emotional syndrome factors in the patients with primary dyslipidemia and the correlations between these factors and blood lipid indexes.MethodsThe general information,information of TCM four examinations related to syndrome factors and blood lipid indexes were collected from the patients(n=120).The syndrome factors were determined and classified according to the theory of syndrome factors differentiation,and statistically analyzed by applying SPSS 17.0 software.ResultsLiver factor had the highest diagnostic rate(77.5%) in 120 patients.The occurrence frequencies of disease-location factors as liver,kidney and spleen were significantly higher than those of other disease-location factors.The occurrence frequencies of disease-nature factors as dampness,qi stagnation,qi deficiency and yin deficiency were significantly higher than those of other disease-nature factors.The levels of high density lipoprotein-cholesterol(HDL-C) and ApoA1 were negatively related to syndrome factors as kidney and yin deficiency,and the levels of HDL-C and ApoA1 had a descending trend with the aggravation of syndrome factors.ConclusionThe major TCM pathogenesis of disease locations of primary dyslipidemia is liver followed by kidney and spleen.The characteristic of disease nature is a mixture of deficiency and excess.The deficiency syndromes are mainly yin deficiency and qi deficiency,while the excess syndromes are mainly dampness and qi stagnation.Liver qi stagnation and liver-kidney yin deficiency are the main pathogenesis of primary dyslipidemia related to TCM emotional theory.The reductions of HDL-C and ApoA1 levels are most probably related to kidney(location) and yin deficiency(nature).
WANG Wen-rong,ZHAO Yin-long,SHAN Jing-wen,ZHANG Wei,YE Qing-jing,YE Zhi-ying,CHEN Hua,LIN Hua-fang
Vol. 20, Issue 6, Pages: 23-27(2013)
摘要:Objective To study the curative effect of acupuncture recipe with the actions of fortifying spleen and reducing lipid on obesity patients induced by spleen deficiency and exuberant dampness,and its influence on patients’ fasting blood fat.MethodsAccording to the principles of randomized controlled trials,all patients were divided into treatment group(n=62) and control group(n=20).Treatment group was treated with modified acupuncture recipe,which included Neiting(S44),Gongsun(SP4),Zusanli(ST36),Zhongwan(CV12) and Fenglong(S40).Control group was treated with acupuncture in eight points around umbilicus,which included bilateral Huaroumen(ST24),Tianshu(S25),Wailing(ST26),Shuifen(RN9) and Yinjiao(RN7).A therapeutic course was 10 days and all groups were treated for 3 therapeutic courses.The curative effect and changes of patients’ weight,body mass index(BMI),waistline,hipline and fasting blood fat were observed before and after treatment.Results ①Patients’ weight,BMI,waistline and hipline had statistical differences in two groups before and after treatment(P<0.05).The levels of serum total cholesterol(TC) and triglyceride(TG) had statistical differences in treatment group before and after treatment(P<0.05).②The total clinical effective rate had statistical difference between two groups(P<0.05).③ The patients’ weight and hipline(P<0.05),BMI(P<0.01) and TC and TG(P<0.05) had statistical differences between two groups after treatment.ConclusionThe curative effect of acupuncture recipe with the actions of fortifying spleen and reducing lipid is better than that of acupuncture in eight points around umbilicus in obesity patients induced by spleen deficiency and exuberant dampness,and the former can decrease patients’ weight,BMI,hipline and levels of TC and TG.
关键词:fortifying spleen and reducing lipid;acupuncture;obesity;spleen deficiency and exuberant dampness
摘要:ObjectiveTo discuss the curative effect of Fufang Ejiao Jiang on cancer related anemia.Methods Patients(n=98) were randomly divided into control group(treated with conventional therapy,n=40) and treatment group(treated with conventional therapy and Fufang Ejiao Jiang,n=50).The changes of TCM symptom integrals and periphery hemogram were observed before and after treatment.Results①The levels of RBC and HGB were higher in each group after treatment,and the curative effect was not better in treatment group than that in control group.② On the 3rd and the 4th weeks,the curative effects on RBC and HGB were better in the patients undergoing chemotherapy in treatment group than those in control group.③On the 3rd and the 4th weeks,the levels of RBC and HGB increased in the patients not undergoing chemotherapy after treatment.On the 4th week,the levels of RBC and HGB increased in control group after treatment.On the 3rd and 4th weeks,the curative effects on RBC and HGB were better in treatment group than those in control group.④The results of ameliorating symptoms were better in treatment group than those in control group.ConclusionFufang Ejiao Jiang has the protective effect on hemogram in the patients undergoing chemotherapy,and can recover the level of haemoglobin and relieve symptoms.
关键词:cancer related anemia;Fufang Ejiao Jiang;TCM treatment
摘要:According to the order of impact factors of Science Citation Index(SCI),the authors have introduced briefly the international journals of Chinese medicine/integrative medicine included by SCI,and the main content included the date of the first issue,chief editor,sponsors,frequency,paper types,contribution requirements,databases,SCI impact factors and websites in 2012 of these journals.The purpose is to provide the reference for TCM researchers to publish high-level English papers.
关键词:journals of Chinese medicine;journals of integrative medicine;Science Citation Index
摘要:Objective To review objectively the definite curative effect of Suxiao Jiuxin Wan on primary dysmenorrheal.MethodsSuxiao Jiuxin Wan group(n=43) was treated with sublingual Suxiao Jiuxin Wan,Fenbid group(n=41),with oral Fenbid Capsules,and Yueyueshu Granules group(n=29),with Yueyueshu Granules.ResultsThe total effective rate was 90.70% in Suxiao Jiuxin Wan group,80.49% in Fenbid group and 100.00% in Yueyueshu Granules group.The onset time of medicinal is significantly shorter in Suxiao Jiuxin Wan group than that in other two groups,and the symptoms of primary dysmenorrheal were significantly relieved in Suxiao Jiuxin Wan group.ConclusionSuxiao Jiuxin Wan has the reliable curative effect on primary dysmenorrheal.
摘要:Objective To observe the influence of needle retention time on the curative effect of acupuncture in the patients with non-organic insomnia.MethodsThe patients(n=60) were randomly divided into treatment group and control group(each n=30) by using random digits table.The two groups were all given acupuncture in Baihui(DU20),Shenting(DU24),Benshen(GB13),Anmian,Shenmen(HT7),Neiguan(PC6),Zusanli(ST36),Sanyinjiao(SP6) and Taichong(LR3) once a day,excluding Saturdays and Sundays,for a total of 20 times.The needle retention time was 20 minutes in treatment group and 40 minutes in control group.The scores were recorded by applying the Pittsburgh sleep quality index(PSQI) respectively before treatment and after treatment for 10 times and 20 times.The results of PSQI were analyzed and the difference in curative effect was reviewed.ResultsAfter treatment for 20 times,the total scores of PSQI had no significant difference between two groups(P>0.05).The total scores of PSQI had significant difference in each group before treatment and after treatment for 20 times(P<0.05).ConclusionThe needle retention time(20 minutes or 40 minutes) has no significant difference on the curative effect of acupuncture on insomnia.
摘要:Objective To discuss the curative effect and safety of the therapy of integrated Chinese and Western medicine on type 2 diabetes.MethodsThe patients with type 2 diabetes(n=80) were randomly divided into treatment group(n=42) and control group(n=38) by using random digits table.The two groups were given the same basic therapy and corresponding treatments such as hypoglycemic therapy,hypotension therapy,anticoagulation therapy and improving cardio-cerebral blood circulation.Control group was given additionally oral Pioglitazone Hydrochloride Capsules(30 mg) once a day,and treatment group was given additionally Chinese medicinal decoction once a day.ResultsThere was significant difference in the total effective rate between two groups.The curative effects of controlling blood sugar,decreasing body mass index and level of cholesterol,and increasing level of high-density lipoprotein were better in treatment group than those in control group,especially the effect of controlling microalbuminuria was greatly significant in treatment group.ConclusionThe therapy of integrated Chinese and Western medicine has significant,safe and stable curative effect in the patients with type 2 diabetes(dampness-heat encumbering spleen syndrome).
关键词:type 2 diabetes;syndrome of dampness-heat encumbering spleen;lipid metabolism;insulin resistance
摘要:Objective To discuss the curative effect of ZHAO Bing-nan’s Quanchong Fang on stubborn dampness gathering.MethodsThe patients with stubborn dampness gathering(n=128) were randomly divided into two groups(each n=64).Control group was treated with oral thalidomide(50 mg) 3 times daily,and treatment group was treated with modified ZHAO Bing-nan’s Quanchong Fang after being differentiated into dampness-heat accumulation syndrome and blood stasis and wind-dryness syndrome.ResultsThe effective rate was 97% in treatment group and 81% in control group,and there was statistically significant between two groups.ConclusionZHAO Bing-nan’ s Quanchong Fang has sound curative effects on stubborn dampness gathering.